rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone

Base Information

Chemical Name:rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone
CAS No.:945390-23-8
Molecular Formula:C₂₀H₁₉N₃O₃S
Molecular Weight:381.455
Hs Code.:

Synonyms:rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone

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Technology Process of rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone

There total 1 articles about rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 945390-22-7
rac-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinoline-4-carboxylic acid methoxy-methyl-amide

: 61278-81-7
1-(diethoxymethyl)-1H-imidazole

: 945390-23-8
rac-(1H-imidazol-2-yl)-[1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-4-yl]-methanone

Guidance literature:: 1-(diethoxymethyl)-1H-imidazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

rac-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinoline-4-carboxylic acid methoxy-methyl-amide; In tetrahydrofuran; hexane; at 0 ℃; for 1h;

With hydrogenchloride; water; sodium hydrogencarbonate; more than 3 stages;