(-)-Dihydro-α-cyperone

Base Information

• Chemical Name: (-)-Dihydro-α-cyperone
• CAS No.: 10064-31-0
• Molecular Formula: C₁₅H₂₄O
• Molecular Weight: 220.355
• Mol file: 10064-31-0.mol

Synonyms:(-)-Dihydro-α-cyperone

Chemical Property of (-)-Dihydro-α-cyperone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-Dihydro-α-cyperone

There total 1 articles about (-)-Dihydro-α-cyperone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (R)-7-Isopropenyl-1,4a-dimethyl-octahydro-naphthalen-2-one (10064-31-0,28290-27-9,78780-16-2,97371-98-7,132983-05-2,141902-30-9,145512-83-0)

Guidance literature:

Alkohol VIII, Jones-Reagenz;

DOI:10.1021/jo00885a012

Reference yield:

(-)-Dihydro-α-cyperone (10064-31-0) → α-selinene (473-13-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / LAH, t-BuOH / tetrahydrofuran / 18 h / 0 - 20 °C

2: 88 percent / PPh₃-NCS / tetrahydrofuran / 3 h

3: 86 percent / LiBr, Li₂CO₃ / dimethylformamide / 5 h / 138 - 140 °C

With N-chloro-succinimide; lithium aluminium tetrahydride; lithium carbonate; triphenylphosphine; lithium bromide; tert-butyl alcohol; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/S0957-4166(98)00184-0

Reference yield:

(-)-Dihydro-α-cyperone (10064-31-0) → (+)-chrysanthemol (113773-90-3)

Guidance literature:

Multi-step reaction with 7 steps

1.1: 92 percent / LiAl(OtBu)3H / tetrahydrofuran / 18 h / 20 °C

2.1: N-chlorosuccinimide / tetrahydrofuran / 20 °C

2.2: 88 percent / PPh₃ / tetrahydrofuran / 3 h / 20 °C

3.1: 94 percent / m-CPBA / CH₂Cl₂ / 0.67 h / 20 °C

4.1: 92 percent / LiAlH₄ / diethyl ether / 10 h / 20 °C

5.1: 90 percent / LiBr; Li₂CO₃ / dimethylformamide / 5 h / 138 - 140 °C

6.1: 82 percent / m-CPBA; NaHCO₃ / CH₂Cl₂ / 0.5 h / 0 °C

7.1: 50 percent / Bu₄NI; BF₃*Et₂O / CHCl₃ / 0.17 h / 0 °C

With N-chloro-succinimide; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; tetra-(n-butyl)ammonium iodide; lithium carbonate; sodium hydrogencarbonate; lithium tri-t-butoxyaluminum hydride; 3-chloro-benzenecarboperoxoic acid; lithium bromide; In tetrahydrofuran; diethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide;

DOI:10.1002/jccs.200100042

Downstream raw materials:

r-eudesmol

(+)-chrysanthemol

2-[(2R,4aR,8aR)-4a,8-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-2-yl]acrylaldehyde

(+)-Eudesma-3,11⁽¹³⁾-dien-12-oic acid