Technology Process of methyl 2-(5-mesityl-1-methyl-1H-indol-3-yl)acetate
There total 3 articles about methyl 2-(5-mesityl-1-methyl-1H-indol-3-yl)acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium dichloride;
In
1,4-dioxane;
at 100 ℃;
for 67h;
Inert atmosphere;
DOI:10.1002/anie.201103151
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: potassium phosphate; 1,1'-bis-(diphenylphosphino)ferrocene; palladium dichloride / 1,4-dioxane / 67 h / 100 °C / Inert atmosphere
With
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; sodium hydride; palladium dichloride;
In
1,4-dioxane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201103151
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: methanol / 0 - 20 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere
2.2: 0 - 20 °C / Inert atmosphere
3.1: potassium phosphate; 1,1'-bis-(diphenylphosphino)ferrocene; palladium dichloride / 1,4-dioxane / 67 h / 100 °C / Inert atmosphere
With
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; sodium hydride; palladium dichloride;
In
1,4-dioxane; methanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1002/anie.201103151
