δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure

Base Information

• Chemical Name: δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure
• CAS No.: 104351-44-2
• Molecular Formula: C₃₃H₃₃NO₃P₂
• Molecular Weight: 553.577
• Mol file: 104351-44-2.mol

Synonyms:δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure

Chemical Property of δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure

There total 3 articles about δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,5-pentanedioic acid (110-94-1) + (3R,4R)-3,4-bis(diphenylphosphanyl)pyrrolidine (99135-90-7,145693-67-0) → δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure (104351-44-2)

Guidance literature:

In diethyl ether; dichloromethane;

Reference yield:

sodium diphenylphosphide (4376-01-6) → δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure (104351-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethylformamide / 24 h / -15 °C

2: toluene / 14 h

In N,N-dimethyl-formamide; toluene;

Reference yield:

glutaric anhydride, (108-55-4) + (3R,4R)-3,4-bis(diphenylphosphanyl)pyrrolidine (99135-90-7,145693-67-0) → δ-<(3R,4R)-3,4-Bis(diphenylphophino)pyrrolidino>-δ-oxopentansaeure (104351-44-2)

Guidance literature:

In toluene; for 14h; Yield given;

upstream raw materials:

glutaric anhydride,

(3R,4R)-3,4-bis(diphenylphosphanyl)pyrrolidine

sodium diphenylphosphide

1,5-pentanedioic acid

Downstream raw materials:

(δ-[(3R,4R)-3,4-bis(diphenylphosphino)-1-pyrrolidino]-δ-oxovaleric acid-P,P')(1,5-cyclooctadiene)rhodium-tetrafluoroborate * 1.5 methanol