(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone

Base Information

Chemical Name:(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone
CAS No.:1312941-98-2
Molecular Formula:C₁₄H₈BrF₂N₃O
Molecular Weight:352.138
Hs Code.:
Mol file:1312941-98-2.mol

Synonyms:(3-amino-2,6-difluorophenyl)-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

Suppliers and Price of (3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone 95%+
1g
$ 980.00

Chemenu
(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone 95%+
250mg
$ 280.00

Chemenu
(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone 95%+
100mg
$ 120.00

Total 6 raw suppliers

Chemical Property of (3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone

Chemical Property:

PKA:10.55±0.40(Predicted)
Density:1.759±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

(3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone

There total 7 articles about (3-Amino-2,6-difluorophenyl)(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.65%

: (2,6-difluoro-3-nitrophenyl)-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

: 1312941-98-2
(3-amino-2,6-difluorophenyl)-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

Guidance literature:: With tin(ll) chloride; In 2-methyltetrahydrofuran; at 60 ℃; Large scale;

Reference yield:

: 918521-11-6
[3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-carbamic acid methyl ester

: 1312941-98-2
(3-amino-2,6-difluorophenyl)-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

Guidance literature:: With trimethylsilyl iodide; In acetonitrile; at 20 ℃; Inert atmosphere;

Reference yield:

: 260552-98-5
2,6-difluoro-3-nitrobenzoic acid chloride

: 1312941-98-2
(3-amino-2,6-difluorophenyl)-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride / 1,2-dichloro-ethane / 1.5 h / 45 - 50 °C / Large scale

2: tin(ll) chloride / 2-methyltetrahydrofuran / 60 °C / Large scale

With aluminum (III) chloride; tin(ll) chloride; In 2-methyltetrahydrofuran; 1,2-dichloro-ethane;