(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

Base Information

Chemical Name:(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid
CAS No.:250600-98-7
Molecular Formula:C₂₆H₂₂N₂O₅
Molecular Weight:442.471
Hs Code.:

Synonyms:(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

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Chemical Property of (Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

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Technology Process of (Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

There total 5 articles about (Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [(Z)-4-(5-Methyl-2-phenyl-oxazol-4-ylmethoxy)-benzyloxyimino]-phenyl-acetic acid methyl ester

: 250600-98-7
(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; at 40 ℃; for 1h;
DOI:10.1248/cpb.50.1349

Reference yield:

: 103789-66-8
4-(5-methyl-2-phenyl-4-oxazolylmethoxy)-benzaldehyde

: 250600-98-7
(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / NaBH₄ / methanol; tetrahydrofuran / 0.5 h / 20 °C

2: 99 percent / SOCl₂ / toluene / 0.5 h / 20 °C

3: NaH / dimethylformamide / 20 °C

4: aq. NaOH / tetrahydrofuran; methanol / 1 h / 40 °C

With sodium hydroxide; sodium tetrahydroborate; thionyl chloride; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1248/cpb.50.1349

Reference yield:

: 250602-53-0
4-{[4-(chloromethyl)phenoxy]methyl}-5-methyl-2-phenyl-1,3-oxazole

: 250600-98-7
(Z)-2-{4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyimino}-2-phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 20 °C

2: aq. NaOH / tetrahydrofuran; methanol / 1 h / 40 °C

With sodium hydroxide; sodium hydride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.50.1349