(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Base Information

Chemical Name:(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester
CAS No.:808148-57-4
Molecular Formula:C₃₇H₄₂O₈
Molecular Weight:614.736
Hs Code.:

Synonyms:(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Suppliers and Price of (S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

There total 5 articles about (S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3162-96-7
methyl 4,6-O-benzylidene-α-D-glucopyranoside

: 808148-57-4
(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: Bu₂SnO / benzene; methanol / 12 h / 85 °C

1.2: 80 percent / dioxane / 20 °C

2.1: 95 percent / EDCI; DMAP / CH₂Cl₂ / 20 °C

3.1: aq. AcOH / 10 h / 80 °C

4.1: DMAP; pyridine / 15 h / 80 °C

With pyridine; dmap; di(n-butyl)tin oxide; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; dichloromethane; benzene;
DOI:10.1021/ja048170p

Reference yield:

: 39716-58-0
pent-4-enoyl chloride

: 808148-57-4
(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: Bu₂SnO / benzene; methanol / 12 h / 85 °C

1.2: 80 percent / dioxane / 20 °C

2.1: 95 percent / EDCI; DMAP / CH₂Cl₂ / 20 °C

3.1: aq. AcOH / 10 h / 80 °C

4.1: DMAP; pyridine / 15 h / 80 °C

With pyridine; dmap; di(n-butyl)tin oxide; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; dichloromethane; benzene;
DOI:10.1021/ja048170p

Reference yield:

: 808148-55-2
Pent-4-enoic acid (4aR,6S,7R,8S,8aS)-8-hydroxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester

: 808148-57-4
(S)-2-Methyl-pent-4-enoic acid (2R,3R,4S,5R,6S)-3-hydroxy-6-methoxy-5-pent-4-enoyloxy-2-trityloxymethyl-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / EDCI; DMAP / CH₂Cl₂ / 20 °C

2: aq. AcOH / 10 h / 80 °C

3: DMAP; pyridine / 15 h / 80 °C

With pyridine; dmap; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;
DOI:10.1021/ja048170p