(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Base Information

Chemical Name:(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran
CAS No.:144617-43-6
Molecular Formula:C₃₄H₅₂O₃SSi₂
Molecular Weight:597.022
Hs Code.:

Synonyms:(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Suppliers and Price of (2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

There total 8 articles about (2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 144617-42-5
(2'S,4'S)-6-(4-tert-Butyldiphenylsilyloxy-2-hydroxyhept-6-enyl)-3,4-dihydro-2H-thiopyran

: 144617-43-6
(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 14h; Ambient temperature;

Reference yield:

: 87318-97-6
(2S)-1-[(4S)-2,2-dimethyl[1,3]dioxolan-4-yl]pent-4-en-2-ol

: 144617-43-6
(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Guidance literature:: Multi-step reaction with 6 steps

1: 94 percent / imidazole, 4-dimethylaminopyridine / dimethylformamide / 18 h / Ambient temperature

2: 100 percent / 80percent aq.HOAc / 8 h / Ambient temperature

3: 96 percent / 4-N,N-dimethylaminopyridine, pyridine / 6 h / Ambient temperature

4: 82 percent / K₂CO₃ / methanol / 2 h / Ambient temperature

5: 86 percent / BF₃*OEt₂ / tetrahydrofuran / 0.17 h / -78 °C

6: 97 percent / diisopropylethylamine / CH₂Cl₂ / 14 h / Ambient temperature

With pyridine; 1H-imidazole; dmap; boron trifluoride diethyl etherate; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: C₅H₇LiS

: 144617-43-6
(2'S,4'S)-6-<4-tert-Butyldiphenylsilyloxy-2-(2-trimethylsilylethoxy)methoxyhept-6-enyl>-3,4-dihydro-2H-thiopyran

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / BF₃*OEt₂ / tetrahydrofuran / 0.17 h / -78 °C

2: 97 percent / diisopropylethylamine / CH₂Cl₂ / 14 h / Ambient temperature

With boron trifluoride diethyl etherate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;