3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

Base Information

Chemical Name:3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde
CAS No.:1065331-90-9
Molecular Formula:C₂₀H₁₆F₃NO₃
Molecular Weight:375.347
Hs Code.:

Synonyms:3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

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Chemical Property of 3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

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Technology Process of 3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

There total 1 articles about 3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 477541-30-3
methanesulfonic acid 2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethyl ester

: 100-83-4
meta-hydroxybenzaldehyde

: 1065331-90-9
3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 48h;

Reference yield: 32.0%

: 1065331-90-9
3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

: 65983-36-0
chlorhydrate de L-thiazolidine carboxylate de methyle

: 1065331-94-3
(R)-3-(3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzyl)thiazolidine-4-carboxylic acid methyl ester

Guidance literature:: With sodium tris(acetoxy)borohydride; triethylamine; In 1,2-dichloro-ethane; for 168h;

Reference yield:

: 1065331-90-9
3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzaldehyde

: 1065331-93-2
(R)-3-(3-(2-(5-methyl-2-(4-trifluoromethylphenyl)oxazol-4-yl)ethoxy)benzyl)thiazolidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride; triethylamine / 1,2-dichloro-ethane / 168 h

2: methanol; lithium hydroxide / 18 h / Heating / reflux

With methanol; lithium hydroxide; sodium tris(acetoxy)borohydride; triethylamine; In 1,2-dichloro-ethane;