(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Base Information

Chemical Name:(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid
CAS No.:911370-71-3
Molecular Formula:C₁₂H₁₆BFO₄
Molecular Weight:254.066
Hs Code.:

Synonyms:(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Suppliers and Price of (5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(3-Fluoro-5-(methoxycarbonyl)-2-methylphenyl)boronicacid 97%
5g
$ 1060.00

Crysdot
(3-Fluoro-5-(methoxycarbonyl)-2-methylphenyl)boronicacid 97%
1g
$ 353.00

Alichem
3-Fluoro-5-(methoxycarbonyl)-2-methylphenylboronicacid
5g
$ 1125.00

Activate Scientific
(3-Fluoro-5-(methoxycarbonyl)-2-methylphenyl)boronicacid 97%
1 g
$ 460.00

Total 5 raw suppliers

Chemical Property of (5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Chemical Property:

Boiling Point:401.7±55.0 °C(Predicted)
Density:1.19±0.1 g/cm3(Predicted)

Purity/Quality:

98%Min ^*data from raw suppliers

(3-Fluoro-5-(methoxycarbonyl)-2-methylphenyl)boronicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

There total 3 articles about (5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 861905-85-3
1,1-dimethylethyl 3-fluoro-5-iodo-4-methylbenzoate

: 121-43-7,63156-11-6
Trimethyl borate

: 911370-71-3
(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Guidance literature:: 1,1-dimethylethyl 3-fluoro-5-iodo-4-methylbenzoate; With isopropylmagnesium chloride; In tetrahydrofuran; at -10 - 0 ℃; for 1.66667h;

Trimethyl borate; In tetrahydrofuran; at 0 ℃; for 0.0833333h;

Reference yield:

: 861905-94-4
3-fluoro-5-iodo-4-methylbenzoic acid

: 911370-71-3
(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 1 - 2 h / 0 - 20 °C

1.2: 1 h / 0 - 20 °C

2.1: isopropylmagnesium chloride / tetrahydrofuran / 1.67 h / -10 - 0 °C

2.2: 0.08 h / 0 °C

With oxalyl dichloride; isopropylmagnesium chloride; N,N-dimethyl-formamide; In tetrahydrofuran;

Reference yield:

: 350-28-7
3-fluoro-4-methyl-benzoic acid

: 911370-71-3
(5-{[(1,1-dimethylethyl)oxy]carbonyl}-3-fluoro-4-methylphenyl)boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-iodo-succinimide / trifluorormethanesulfonic acid / 99.5 h / -15 - 0 °C

2.1: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 1 - 2 h / 0 - 20 °C

2.2: 1 h / 0 - 20 °C

3.1: isopropylmagnesium chloride / tetrahydrofuran / 1.67 h / -10 - 0 °C

3.2: 0.08 h / 0 °C

With N-iodo-succinimide; oxalyl dichloride; isopropylmagnesium chloride; N,N-dimethyl-formamide; In tetrahydrofuran; trifluorormethanesulfonic acid;