methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate

Base Information

• Chemical Name: methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate
• CAS No.: 1000701-09-6
• Molecular Formula: C₂₈H₃₀O₁₁
• Molecular Weight: 542.54
• Mol file: 1000701-09-6.mol

Synonyms:methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate

Chemical Property of methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate

There total 2 articles about methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

(R)-2-(4'-biphenylyl)propanoic acid (10516-54-8) + 1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester (21085-72-3) → methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate (1000701-09-6)

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1021/jo701547b

Reference yield:

2-(4-biphenylyl)propanoic acid (6341-72-6,10516-54-8,10532-14-6,92937-21-8) + 1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester (21085-72-3) → methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate (1000701-09-6) + methyl 2,3,4-tri-O-acetyl-1-O-{(2S)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 2h; Title compound not separated from byproducts.;

DOI:10.1021/jo701547b

Reference yield:

methyl 2,3,4-tri-O-acetyl-1-O-{(2R)-2-(4-biphenylyl)}propionyl-β-D-glucopyranuronate (1000701-09-6) → methyl 1-O-[(2R)-2-(4-biphenylyl)propionyl]-β-D-glucopyranuronate + (R)-2-(4'-biphenylyl)propanoic acid (10516-54-8)

Guidance literature:

With sodium citrate; In water; dimethyl sulfoxide; at 50 ℃; for 4h; pH=5.0;

DOI:10.1021/jo701547b

upstream raw materials:

2-(4-biphenylyl)propanoic acid

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

(R)-2-(4'-biphenylyl)propanoic acid

Downstream raw materials:

(R)-2-(4'-biphenylyl)propanoic acid