4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester

Base Information

• Chemical Name: 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester
• CAS No.: 947495-12-7
• Molecular Formula: C₁₄H₁₈S₂Si
• Molecular Weight: 278.514
• Mol file: 947495-12-7.mol

Synonyms:4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester

Chemical Property of 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester

There total 2 articles about 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[(trimethylsilyl)ethynyl]dithiobenzoic acid 2-(trimethylsilyl)ethyl ester (947495-11-6) → 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester (947495-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Bu₄NF / tetrahydrofuran / 0.33 h / 0 °C

2: 58 mg / tetrahydrofuran / 24 h / 20 °C

With tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1021/ol070789j

Reference yield:

C9H6S2 + (2-bromoethyl)trimethylsilane (18156-67-7) → 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester (947495-12-7)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1021/ol070789j

Reference yield: 66.0%

p-nitrobenzene iodide (636-98-6) + 4-ethynyl(dithiobenzoic) acid 2-(trimethylsilyl)ethyl ester (947495-12-7) → 4-[(4-nitrophenyl)ethynyl]dithiobenzoic acid 2-(trimethylsilyl)ethyl ester

Guidance literature:

With diisopropylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 60 ℃; for 20h;

DOI:10.1021/ol070789j

upstream raw materials:

(2-bromoethyl)trimethylsilane

4-[(trimethylsilyl)ethynyl]dithiobenzoic acid 2-(trimethylsilyl)ethyl ester