8-Quinolinamine, 6-phenyl-

Base Information

Chemical Name:8-Quinolinamine, 6-phenyl-
CAS No.:68527-71-9
Molecular Formula:C15H12N2
Molecular Weight:220.274
Hs Code.:
DSSTox Substance ID:DTXSID1071614
Nikkaji Number:J441.186B
Wikidata:Q81999327
Mol file:68527-71-9.mol

Synonyms:6-Phenyl-8-quinolinamine;68527-71-9;8-Quinolinamine, 6-phenyl-;6-phenylquinolin-8-amine;8-Amino-6-phenylquinoline;DTXSID1071614

Suppliers and Price of 8-Quinolinamine, 6-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 8-Quinolinamine, 6-phenyl-

Chemical Property:

Vapor Pressure:1.21E-07mmHg at 25°C
Boiling Point:431.4°C at 760 mmHg
Flash Point:244.6°C
PSA：38.91000
Density:1.194g/cm³
LogP:4.06520
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:220.100048391
Heavy Atom Count:17
Complexity:247

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)N

Technology Process of 8-Quinolinamine, 6-phenyl-

There total 4 articles about 8-Quinolinamine, 6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 68527-70-8
6-phenyl-8-nitroquinoline

: 68527-71-9
6-phenyl-8-aminoquinoline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; Inert atmosphere; Schlenk technique; Glovebox;
DOI:10.1002/zaac.201800258

Reference yield:

: 4075-79-0
4-phenylacetanilide

: 68527-71-9
6-phenyl-8-aminoquinoline

Guidance literature:: Multi-step reaction with 4 steps

1.1: nitric acid; acetic acid / 1 h / 70 °C / Inert atmosphere; Schlenk technique; Glovebox

2.1: water; potassium hydroxide / ethanol / 0.33 h / 80 °C / Schlenk technique; Inert atmosphere; Glovebox

3.1: chloranil; hydrogenchloride / butan-1-ol; water / 113 °C / Inert atmosphere; Schlenk technique; Glovebox

3.2: 113 °C / Inert atmosphere; Schlenk technique; Glovebox

4.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / Inert atmosphere; Schlenk technique; Glovebox

With hydrogenchloride; palladium 10% on activated carbon; water; hydrogen; nitric acid; chloranil; acetic acid; potassium hydroxide; In methanol; ethanol; water; butan-1-ol;
DOI:10.1002/zaac.201800258

Reference yield:

: 4085-18-1
4-amino-3-nitrobiphenyl

: 68527-71-9
6-phenyl-8-aminoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloranil; hydrogenchloride / butan-1-ol; water / 113 °C / Inert atmosphere; Schlenk technique; Glovebox

1.2: 113 °C / Inert atmosphere; Schlenk technique; Glovebox

2.1: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 20 °C / Inert atmosphere; Schlenk technique; Glovebox

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; chloranil; In methanol; water; butan-1-ol;
DOI:10.1002/zaac.201800258