Technology Process of C15H16O4
There total 10 articles about C15H16O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
for 1h;
DOI:10.1021/ol401730d
- Guidance literature:
-
Multi-step reaction with 9 steps
1: pyridine; dmap / 16 h / 20 °C
2: hydrogenchloride / dichloromethane / 17 h / 0 - 15 °C / Sealed tube
3: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / toluene / 2 h / Heating
4: ammonia / methanol / 16 h / 20 °C / Sealed tube
5: camphorsulphonic acid / N,N-dimethyl-formamide / 4 h / 55 °C
6: 2,3-dicyano-5,6-dichloro-p-benzoquinone; water / dichloromethane / 16 h
7: pyridine / 96 h
8: sodium methylate / dichloromethane; methanol / 24 h / 20 °C
9: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h
With
pyridine; hydrogenchloride; dmap; 2,2'-azobis(isobutyronitrile); ammonia; water; tri-n-butyl-tin hydride; sodium methylate; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
methanol; dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/ol401730d
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / toluene / 2 h / Heating
2: ammonia / methanol / 16 h / 20 °C / Sealed tube
3: camphorsulphonic acid / N,N-dimethyl-formamide / 4 h / 55 °C
4: 2,3-dicyano-5,6-dichloro-p-benzoquinone; water / dichloromethane / 16 h
5: pyridine / 96 h
6: sodium methylate / dichloromethane; methanol / 24 h / 20 °C
7: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h
With
pyridine; 2,2'-azobis(isobutyronitrile); ammonia; water; tri-n-butyl-tin hydride; sodium methylate; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
methanol; dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/ol401730d
