2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

Base Information

Chemical Name:2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid
CAS No.:647863-29-4
Molecular Formula:C₂HF₃O₂*C₁₄H₁₁ClF₃N₃
Molecular Weight:427.734
Hs Code.:

Synonyms:2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

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Technology Process of 2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

There total 1 articles about 2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 647863-27-2
tert-butyl 2-(4-chlorophenyl)-4-(trifluoromethyl)-5,8-dihydropyrido[3,4-d]pyrimidine-7 (6H)-carboxylate

: 76-05-1
trifluoroacetic acid

: 647863-29-4
2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

Guidance literature:: In dichloromethane; at 20 ℃; for 0.75h;

Reference yield:

: 647863-29-4
2-(4-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine trifluoroacetic acid

: 486459-98-7
(3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid

: C₂₉H₂₈ClF₅N₄O₃

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h;