4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Base Information

Chemical Name:4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid
CAS No.:1239956-70-7
Molecular Formula:C₂₆H₁₉Cl₂F₃N₂O₂S
Molecular Weight:551.416
Hs Code.:

Synonyms:4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Suppliers and Price of 4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Hazard Codes:

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Technology Process of 4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

There total 4 articles about 4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1239956-67-2
4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzonitrile

: 1239956-70-7
4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Guidance literature:: With sulfuric acid; water; at 110 ℃; for 8h;

Reference yield:

: 228421-83-8
3,5-difluoro-4-(hydroxymethyl)benzonitrile

: 1239956-70-7
4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus tribromide / dichloromethane / 1 h / 0 °C

2: potassium carbonate / acetone / 4 h / 56 °C

3: sulfuric acid; water / 8 h / 110 °C

With sulfuric acid; water; phosphorus tribromide; potassium carbonate; In dichloromethane; acetone;

Reference yield:

: 1239964-16-9
4-(bromomethyl)-3,5-difluorobenzonitrile

: 1239956-70-7
4-((5-(2-(3,4-dichlorophenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-3,5-difluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 4 h / 56 °C

2: sulfuric acid; water / 8 h / 110 °C

With sulfuric acid; water; potassium carbonate; In acetone;