Cabazitaxel-d6

Base Information

Chemical Name:Cabazitaxel-d6
CAS No.:1383561-29-2
Molecular Formula:C₄₅H₅₇NO₁₄
Molecular Weight:841.898
Hs Code.:
Mol file:1383561-29-2.mol

Synonyms:d6-cabazitaxel

Suppliers and Price of Cabazitaxel-d6

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Cabazitaxel-d6
1mg
$ 531.00

TRC
Cabazitaxel-d6(~90%)
1mg
$ 245.00

Medical Isotopes, Inc.
Cabazitaxel-d6
1 mg
$ 490.00

Total 11 raw suppliers

Chemical Property of Cabazitaxel-d6

Chemical Property:

Melting Point:151-158°C
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Cabazitaxel-d6 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Cabazitaxel-d6 is a labelled novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor. Cabazitaxel-d6 can be intended for use as an internal standard for the quantification of Cabazitaxel by GC- or LC-mass spectrometry.

Technology Process of Cabazitaxel-d6

There total 3 articles about Cabazitaxel-d6 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1383561-30-5
2'-triethylsilyl-7β,10β-(d₆)-dimethoxydocetaxel

: 1383561-29-2
d6-cabazitaxel

Guidance literature:: With hydrogenchloride; ethanol; at 0 ℃; Inert atmosphere;

Reference yield:

: 1383325-07-2
7β,10β-(d₆)-dimethoxy-10-deacetylbaccatin III

: 1383561-29-2
d6-cabazitaxel

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; dicyclohexyl-carbodiimide / ethyl acetate / 20 °C / Molecular sieve; Inert atmosphere

2: hydrogenchloride; ethanol / 0 °C / Inert atmosphere

With hydrogenchloride; dmap; ethanol; dicyclohexyl-carbodiimide; In ethyl acetate;

Reference yield:

: 32981-86-5,172018-16-5
10-deacetylbaccatin III

: 1383561-29-2
d6-cabazitaxel

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydride / tetrahydrofuran / 8 h / -20 - 20 °C

2: dmap; dicyclohexyl-carbodiimide / ethyl acetate / 20 °C / Molecular sieve; Inert atmosphere

3: hydrogenchloride; ethanol / 0 °C / Inert atmosphere

With hydrogenchloride; dmap; ethanol; potassium hydride; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethyl acetate;