(3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine

Base Information

• Chemical Name: (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine
• CAS No.: 139025-48-2
• Molecular Formula: C₂₃H₂₁NO₄
• Molecular Weight: 375.424

Synonyms:(3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine

Chemical Property of (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine

There total 37 articles about (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.2%

(2R*,3R*,4aR*,11S*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-chloro-Δ1(11a)-8,9-(methylenedioxy)-5,11-methanomorphanthridine (139025-51-7) → (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ1(11a)-5,11-methanomorphanthridine (139025-48-2)

Guidance literature:

With tetra(n-butyl)ammonium dichromate(VI); In chloroform; for 3h; Heating;

DOI:10.1021/jo00052a051

Reference yield: 26.3%

(3R*,4aR*,11S*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-5,11-methanomorphanthridine (139025-47-1) → (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ1(11a)-5,11-methanomorphanthridine (139025-48-2)

Guidance literature:

With disodium hydrogenphosphate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; for 1h; Heating;

DOI:10.1021/jo00052a051

Reference yield: 26.0%

5,11-methanomorphanthridin-2-one (139025-47-1) → C23H21NO4 (139025-48-2)

Guidance literature:

With disodium hydrogenphosphate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; Heating;

DOI:10.1016/0040-4039(91)85045-7

upstream raw materials:

5,11-methanomorphanthridin-2-one

(3,4-methylenedioxy)phenylmagnesium bromide

(1R*,2S*)-2-<3',4'-(methylenedioxy)benzoyl>-4-cyclohexenecarboxylic acid

(+/-)-2,3-cis-3-benzyloxy-2-hydroxy-4a,11a-cis-11,11a-syn-5,11-methano-8,9-methylenedioxymorphanthrine

Downstream raw materials:

(+/-)-O-benzylcoccinine

(+/-)-coccinine

(3R*,4aR*,11R*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2,2-dimethoxy-Δ^1(11a)-8,9-(methylenedioxy)-5,11-methanomorphanthridine

(+/-)-coccinine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 139025-48-2 (3R*,4aR*,11aR*)-5,11a-cis-11,11a-syn-3-(benzyloxy)-2-oxo-8,9-(methylenedioxy)-Δ^1(11a)-5,11-methanomorphanthridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send