C₇₁H₇₅NO₃

Base Information

• Chemical Name: C₇₁H₇₅NO₃
• CAS No.: 941279-10-3
• Molecular Formula: C₇₁H₇₅NO₃
• Molecular Weight: 990.381
• Mol file: 941279-10-3.mol

Synonyms:C₇₁H₇₅NO₃

Chemical Property of C₇₁H₇₅NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₁H₇₅NO₃

There total 11 articles about C₇₁H₇₅NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C70H74INO2 (941279-08-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → C71H75NO3 (941279-10-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 3h;

DOI:10.1021/jo070210v

Reference yield:

tetraethyl((5-iodo-1,3-phenylene)bis(methylene))bis(phosphonate) (496043-74-4) → C71H75NO3 (941279-10-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 80 percent / t-BuOK / tetrahydrofuran / 2 h / 0 °C

2: 93 percent / t-BuOK / tetrahydrofuran / 2 h / 20 °C

3: 87 percent / nBuLi / tetrahydrofuran / 3 h / -78 - 20 °C

4: 57 percent / t-BuOK / tetrahydrofuran / 2 h / 0 °C

5: 69 percent / t-BuOK / tetrahydrofuran / 2 h / 20 °C

6: 92 percent / nBuLi / tetrahydrofuran / 3 h / -78 - 20 °C

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; 1: Horner-Wadsworth-Emmons reaction / 2: Horner-Wadsworth-Emmons reaction / 4: Horner-Wadsworth-Emmons reaction / 5: Horner-Wadsworth-Emmons reaction;

DOI:10.1021/jo070210v

Reference yield:

{3-[(E)-2-(4-Dibutylamino-phenyl)-vinyl]-5-iodo-benzyl}-phosphonic acid diethyl ester (900791-11-9) → C71H75NO3 (941279-10-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 93 percent / t-BuOK / tetrahydrofuran / 2 h / 20 °C

2: 87 percent / nBuLi / tetrahydrofuran / 3 h / -78 - 20 °C

3: 57 percent / t-BuOK / tetrahydrofuran / 2 h / 0 °C

4: 69 percent / t-BuOK / tetrahydrofuran / 2 h / 20 °C

5: 92 percent / nBuLi / tetrahydrofuran / 3 h / -78 - 20 °C

With n-butyllithium; potassium tert-butylate; In tetrahydrofuran; 1: Horner-Wadsworth-Emmons reaction / 3: Horner-Wadsworth-Emmons reaction / 4: Horner-Wadsworth-Emmons reaction;

DOI:10.1021/jo070210v

upstream raw materials:

C₇₀H₇₄INO₂

N,N-dimethyl-formamide

{3-[(E)-2-(4-Dibutylamino-phenyl)-vinyl]-5-iodo-benzyl}-phosphonic acid diethyl ester

C₃₁H₃₆IN

Downstream raw materials:

C₈₃H₉₁INO₅P

C₈₃H₉₂NO₅P