methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

Base Information

• Chemical Name: methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside
• CAS No.: 257936-78-0
• Molecular Formula: C₇₁H₈₆O₁₇
• Molecular Weight: 1211.45

Synonyms:methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

Chemical Property of methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

There total 8 articles about methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methyl O-(4-O-chloroacetyl-6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (257936-76-8) → methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (257936-78-0)

Guidance literature:

With 2,6-dimethylpyridine; thiourea; In methanol; dichloromethane; Heating;

DOI:10.1071/CH99031

Reference yield:

phenyl 1-thio-β-D-fucopyranoside (1214-98-8) → methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (257936-78-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: TsOH*H₂O / 4 h / 20 °C

2.1: 89 percent / 4-dimethylaminopyridine; pyridine / 20 - 100 °C

3.1: aq. TFA / 20 °C

4.1: Bu₂SnO / benzene / Heating

4.2: 1,2-dichloro-ethane / 1 h / 20 °C

5.1: 89 percent / pyridine / CH₂Cl₂ / 20 °C

6.1: 82 percent / N-iodosuccinimide; TfOH / 1,2-dichloro-ethane; diethyl ether / 20 °C

7.1: 91 percent / thiourea; 2,6-lutidine / CH₂Cl₂; methanol / Heating

With pyridine; 2,6-dimethylpyridine; dmap; N-iodo-succinimide; trifluorormethanesulfonic acid; di(n-butyl)tin oxide; toluene-4-sulfonic acid; thiourea; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane; benzene; 1.1: cyclocondensation / 2.1: Esterification / 3.1: Ring cleavage / 4.1: Cyclization / 4.2: Ring cleavage / 5.1: Acetylation / 6.1: Substitution / 7.1: Deacetylation;

DOI:10.1071/CH99031

Reference yield:

Phenyl-2,3,4-tri-O-acetyl-6-desoxy-1-thio-β-D-galactopyranosid (141193-62-6) → methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (257936-78-0)

Guidance literature:

Multi-step reaction with 8 steps

1.1: NaOMe / methanol

2.1: TsOH*H₂O / 4 h / 20 °C

3.1: 89 percent / 4-dimethylaminopyridine; pyridine / 20 - 100 °C

4.1: aq. TFA / 20 °C

5.1: Bu₂SnO / benzene / Heating

5.2: 1,2-dichloro-ethane / 1 h / 20 °C

6.1: 89 percent / pyridine / CH₂Cl₂ / 20 °C

7.1: 82 percent / N-iodosuccinimide; TfOH / 1,2-dichloro-ethane; diethyl ether / 20 °C

8.1: 91 percent / thiourea; 2,6-lutidine / CH₂Cl₂; methanol / Heating

With pyridine; 2,6-dimethylpyridine; dmap; N-iodo-succinimide; trifluorormethanesulfonic acid; sodium methylate; di(n-butyl)tin oxide; toluene-4-sulfonic acid; thiourea; trifluoroacetic acid; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane; benzene; 1.1: Deacetylation / 2.1: cyclocondensation / 3.1: Esterification / 4.1: Ring cleavage / 5.1: Cyclization / 5.2: Ring cleavage / 6.1: Acetylation / 7.1: Substitution / 8.1: Deacetylation;

DOI:10.1071/CH99031

upstream raw materials:

methyl O-(4-O-chloroacetyl-6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

phenyl 1-thio-β-D-fucopyranoside

Phenyl-2,3,4-tri-O-acetyl-6-desoxy-1-thio-β-D-galactopyranosid

phenyl 6-deoxy-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside

Downstream raw materials:

methyl O-(6-deoxy-2,3-di-O-pivaloyl-4-O-trifluoromethylsulfonyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 257936-78-0 methyl O-(6-deoxy-2,3-di-O-pivaloyl-β-D-galactopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send