4,4'-Bis(hydroxy)-alpha-methylstilbene

Base Information

• Chemical Name: 4,4'-Bis(hydroxy)-alpha-methylstilbene
• CAS No.: 72108-22-6
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• DSSTox Substance ID: DTXSID90873487
• Mol file: 72108-22-6.mol

Synonyms:4,4'-bis(hydroxy)-alpha-methylstilbene;4-[2-(4-hydroxyphenyl)prop-1-enyl]phenol;DTXSID90873487;4,4'-Dihydroxy-alphamethylstilbene;4,4'-dihydroxyl-alpha-methylstilbene;4,4'-(1-Methyl-1,2-ethenediyl)bis[phenol]

Chemical Property of 4,4'-Bis(hydroxy)-alpha-methylstilbene

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 226.099379685
• Heavy Atom Count: 17
• Complexity: 256

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CC1=CC=C(C=C1)O)C2=CC=C(C=C2)O

Technology Process of 4,4'-Bis(hydroxy)-alpha-methylstilbene

There total 6 articles about 4,4'-Bis(hydroxy)-alpha-methylstilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

chloroacetone (78-95-5) + phenol (108-95-2,27073-41-2) → 1,2-bis(4-hydroxyphenyl)-2-hydroxypropane (154928-56-0) + 4,4'-dihydroxy-α-methylstilbene (72108-22-6)

Guidance literature:

chloroacetone; phenol; With methyl bisulfate; In dichloromethane; at -15 - -10 ℃;

With calcium carbonate; In dichloromethane; water; isopropyl alcohol; at 50 ℃; for 4h;

Reference yield: 46.0%

chloroacetone (78-95-5) + phenol (108-95-2,27073-41-2) → 4,4'-dihydroxy-α-methylstilbene (72108-22-6)

Guidance literature:

With sulfuric acid; 1.) 5 deg C, 1 h, 2.) i-PrOH, 43 deg C;

DOI:10.1080/10587259508033628

Reference yield:

1,2-bis(4-hydroxyphenyl)-2-chloropropane (324521-87-1) → 4,4'-dihydroxy-α-methylstilbene (72108-22-6)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 50 - 80 ℃; pH=0.9 - 5.94;

upstream raw materials:

chloroacetone

phenol

1,2-bis(4-hydroxyphenyl)-2-chloropropane

Downstream raw materials:

4,4'-Bis-(2-hydroxy-ethoxy)-α-methyl-stilben

Refernces

• 1、 Giamberini,Amendola,Carfagna. "Liquid crystalline epoxy thermosets". . p. 9 - 22. Retrieved 2007/10/03.
• 2、 Ozcayir, Y.,Asrar, J.,Clough, S. B.,Blumstein, A.. "Diacetylenic Liquid Crystalline Polymers II: Derivatives of 10,12-Docosadiyne-1,22-Dioic Acid". . p. 167 - 178. Retrieved 2007/10/02.