Dha-DA conjugate

Base Information

Chemical Name:Dha-DA conjugate
CAS No.:129024-87-9
Molecular Formula:C₃₀H₄₁NO₃
Molecular Weight:463.66
Hs Code.:
Nikkaji Number:J1.507.296B
ChEMBL ID:CHEMBL343736

Synonyms:4,7,10,13,16,19-docosahexaenoic acid dopamine conjugate;DHA-DA conjugate;N-(2-(3,4-dihydroxyphenyl)ethyl)-4,7,10,13,16,19-docosahexaenamide;NMI 8739;NMI-8739

Suppliers and Price of Dha-DA conjugate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Dha-DA conjugate

Chemical Property:

Vapor Pressure:5.51E-18mmHg at 25°C
Boiling Point:659.2°C at 760 mmHg
Flash Point:352.5°C
Density:1.03g/cm³
XLogP3:5.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:17
Exact Mass:463.30864417
Heavy Atom Count:34
Complexity:687

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)NCCC1=CC(=C(C=C1)O)O
Isomeric SMILES:CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCC1=CC(=C(C=C1)O)O

Technology Process of Dha-DA conjugate

There total 11 articles about Dha-DA conjugate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1220710-23-5
DHA-dopamine(acetonide)

: 129024-87-9
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(3,4-dihydroxyphenethyl)docosa-4,7,10,13,16,19-hexaenamide

Guidance literature:: With toluene-4-sulfonic acid; In chloroform; water; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.tetlet.2010.02.089

Reference yield: 62.0%

: 645-31-8
3-hydroxytyramine hydrobromide

: 98770-66-2
docosahexaenoic acid anhydride

: 129024-87-9
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(3,4-dihydroxyphenethyl)docosa-4,7,10,13,16,19-hexaenamide

Guidance literature:: With dmap; In dichloromethane;
DOI:10.1016/0024-3205(96)00101-4

Reference yield:

: 51-61-6
dopamine

: 6217-54-5
docosahexaenoic acid

: 129024-87-9
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(3,4-dihydroxyphenethyl)docosa-4,7,10,13,16,19-hexaenamide

Guidance literature:: docosahexaenoic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In ethyl acetate; at 20 ℃; for 1h;

dopamine; In ethyl acetate; at 20 ℃; for 12h;
DOI:10.1016/j.bmc.2010.12.046