645-31-8

Basic information

• Product Name: Dopamine
• Synonyms: 2-benzenediol,4-(2-aminoethyl)-hydrobromide;3,4-dihydroxy-phenethylaminhydrobromide;4-(2-aminoethyl)-1,2-benzenediolhydrobromide;usafel-47;3,4-DIHYDROXY-PHENETHYLAMINE HYDROBROMIDE;3-HYDROXYTYRAMINE HYDROBROMIDE;DOPAMINE HYDROBROMIDE;4-(2-aminoethyl)pyrocatechol
• CAS NO: 645-31-8
• Molecular Formula: C8H12BrNO2
• Molecular Weight: 234.09
• EINECS: 200-110-0
• Mol File: 645-31-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 218-220 °C(lit.)
• Boiling Point: 337.7°C at 760 mmHg
• Flash Point: 158°C
• Appearance: /
• Vapor Pressure: 5.27E-05mmHg at 25°C
• CAS DataBase Reference: Dopamine(CAS DataBase Reference)
• NIST Chemistry Reference: Dopamine(645-31-8)
• EPA Substance Registry System: Dopamine(645-31-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-37
• WGK Germany: 3
• RTECS: SH2290150
• Hazardous Substances Data: 645-31-8(Hazardous Substances Data)

Usage

Uses

3-Hydroxytyramine hydrobromide was used in the preparation of dopamine standards to measure the dopamine release and uptake in striatal brain slices from R6/1 HD model mice by fast-scan cyclic voltammetry. It was employed as internal standard in the determination of catecholamines in biological tissues by liquid chromatography.

InChI:InChI=1/C8H11NO2.BrH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4230-93-7 1,2-dimethoxy-4-(2-nitro-vinyl)-benzene 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 635-85-8 homoveratrylamine hydrochloride 
• 54373-56-7 3.4-dimethoxyphenethylamine hydrobromide 

Downstream Products

• 84454-97-7 N-nicotinoyl dopamine 
• 52768-23-7 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 1221686-08-3 1-(4-chlorophenyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 1221686-09-4 1-(3-nitrophenyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 132257-17-1 1-(4-hydroxyphenyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 1221686-10-7 1-(4-methoxyphenyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 1221686-11-8 BrH*C₁₆H₁₇NO₄ 
• 106005-97-4 (2E)-N-[2-(3,4-dihydroxyphenyl)ethyl]-3-(4-hydroxyphenyl)-2-propenamide 
• 62-31-7 dopamine hydrochloride 
• 65427-91-0 6,7-dihydroxy-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid 
• 65846-04-0 N-<2-(3,4-Dihydroxyphenyl)ethyl>trifluoracetamid 
• 1025423-92-0 1-[2-(4-chlorophenyl)ethyl]-3-[2-(3,4-dihydroxyphenyl)ethyl]thiourea 
• 104822-71-1 1-(3,4-dihydroxy)phenethyl-3-carbamoylpyridinium chloride 
• 90057-85-5 Bis-benzyloxycarbonyl-lysyldopamine-15-crown-5 

Relevant articles and documents

Preparation method of dopamine hydrochloride

The invention provides a method which comprises the following steps: taking veratraldehyde as a starting raw material, firstly carrying out condensation reaction with nitromethane to generate 3, 4-dimethoxy-beta-nitrostyrolene, carrying out catalytic reduction to obtain 3, 4-dimethoxy phenylethylamine, carrying out reaction with hydrobromic acid to remove methoxy, and finally salifying with hydrochloric acid to obtain dopamine hydrochloride. The preparation method has the advantages of cheap and easily available initial raw materials, simple process, no high-temperature and high-pressure steps, low cost, high purity and high yield, and is suitable for industrial production.

Method for efficiently preparing 5,6-dihydroxyindole (by machine translation)

The preparation method 5,6 - of the compound,dihydroxyindole comprises the following steps :(1): dissolving 3,4 - dialkoxybenzylethylamine and a catalyst in an organic solvent, in an organic solvent, carrying out reflux reaction, in the heated stirring state ;(2) and then further purifying to obtain (1)-hydroxyindole solid powder, which is suitable for industrial production, and has a high, product purity, stability, and easy long-term storage after the operation steps, are short ;(3) reaction steps, through an oxidation reaction, and then further purifying the intermediate compound I, and then purifying the compound I by the oxidizing agent, and then purifying the intermediate compound. I by using a, reducing agent, and then, purifying the intermediate compound I by the, oxidation reaction step 5,6 - and further, purifying the obtained dopamine white solid, powder . by oxidation reaction . The method comprises the following steps. (by machine translation)