4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Base Information

Chemical Name:4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate
CAS No.:50281-47-5
Molecular Formula:C₃₃H₅₀O₃
Molecular Weight:494.758
Hs Code.:

Synonyms:4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Suppliers and Price of 4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Phyllohydroquinone1-Acetate
2.5mg
$ 1045.00

Total 2 raw suppliers

Chemical Property of 4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Chemical Property:

Purity/Quality:

>95% ^*data from raw suppliers

Phyllohydroquinone1-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Phyllohydroquinone 1-Acetate is an impurity of Vitamin K1 (V676080), a vitamin that occurs widely in green plants, algae, photosynthetic bacteria.

Technology Process of 4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

There total 4 articles about 4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 2211-27-0
4-acetoxy-3-methyl-1-naphthol

: 150-86-7,844467-91-0
phytol

: 50281-47-5
4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Guidance literature:: With boron trifluoride diethyl etherate; In 1,4-dioxane; ethyl acetate; at 50 ℃; for 3h;
DOI:10.1021/ac0489667

Reference yield:

: 573-20-6
menadiol di(acetate)

: 50281-47-5
4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / K₂CO₃; Na₂S₂O₄ / methanol; H₂O / 1 h / 30 - 40 °C

2: 47 percent / BF₃*Et₂O / dioxane; ethyl acetate / 3 h / 50 °C

With sodium dithionite; boron trifluoride diethyl etherate; potassium carbonate; In 1,4-dioxane; methanol; water; ethyl acetate;
DOI:10.1021/ac0489667

Reference yield:

: 58-27-5,34524-96-4
menadione

: 50281-47-5
4-Hydroxy-2-methyl-3-<(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-enyl>naphth-1-yl Acetate

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; palladium on activated charcoal; hydrogen / ethyl acetate / 4 h / 20 °C

2: diisopropylamine / methanol; water / 3 h / 20 - 25 °C

3: boron trifluoride diethyl etherate / diethyl ether / 2 h / 80 °C

With dmap; palladium on activated charcoal; boron trifluoride diethyl etherate; hydrogen; diisopropylamine; In methanol; diethyl ether; water; ethyl acetate;