573-20-6 Usage
Description
Menadiol diacetate, also known as Vitamin K3, is a synthetic derivative of Vitamin K that has been chemically modified to enhance its water solubility. It is a vital component in the synthesis of several proteins involved in blood coagulation and plays a significant role in maintaining the normal blood clotting system.
Uses
Used in Pharmaceutical Industry:
Menadiol diacetate is used as a pharmaceutical agent for the treatment of various bleeding disorders and conditions related to impaired blood clotting. It is particularly effective in managing hemorrhagic conditions and supports the body's natural clotting mechanisms.
Used in Veterinary Medicine:
In the veterinary field, Menadiol diacetate is utilized as a treatment for bleeding issues in animals, similar to its application in humans. It helps in managing and preventing excessive bleeding in various medical and surgical situations.
Used in Research Applications:
Menadiol diacetate is also employed in scientific research as a tool to study the mechanisms of blood coagulation and the role of Vitamin K-dependent proteins in this process. It aids in understanding the underlying factors that contribute to clot formation and related disorders.
Used in Dietary Supplements:
As a synthetic form of Vitamin K, Menadiol diacetate is sometimes included in dietary supplements to support overall health and well-being. It is particularly beneficial for individuals with dietary restrictions or those who may have difficulty obtaining adequate amounts of Vitamin K from their diet alone.
Check Digit Verification of cas no
The CAS Registry Mumber 573-20-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 573-20:
(5*5)+(4*7)+(3*3)+(2*2)+(1*0)=66
66 % 10 = 6
So 573-20-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H14O4/c1-9-8-14(18-10(2)16)12-6-4-5-7-13(12)15(9)19-11(3)17/h4-8H,1-3H3
573-20-6Relevant articles and documents
Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition of in Situ Oxidation-Generated ortho-Quinone Methides and Aldehydes
Zhou, Ding,Yu, Xueting,Zhang, Jian,Wang, Wei,Xie, Hexin
supporting information, p. 174 - 177 (2018/01/17)
An unprecedented chiral secondary amine-catalyzed formal [4 + 2] annulation of aldehydes and oxidation-generated β-unsubstituted o-QMs is reported. This asymmetric protocol allows direct functionalization of the benzylic C-H bonds and furnishes [4 + 2] cycloadducts, chromanols, with excellent enantioselectivity and in up to 92% yield. The usability of this approach was further demonstrated by the enantioselective synthesis of anticancer Rhinacanthins derivative NKPLS8.
A METHOD OF MAKING VITAMIN K1
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Paragraph 0049-0051, (2017/03/28)
This invention discloses a method of making vitamin K1. The mentioned method of making vitamin K1 comprises performing a first one-pot synthesis with base catalyst, performing a first hydrolysis, performing a substitution, and performing a second one-pot synthesis for oxidation reaction without using metal oxidant. The starting material of this invention is stable 2-methyl-1,4-naphthoquinone. Preferably, this invention provides a method of making vitamin K1 efficiently on simplifying the operation and decreasing the formation of side-product. More preferably, without the usage of metal residue in this invention results that the vitamin K1 is more safety for clinical application.
The regioselective synthesis of monomethoxynaphthylene diacetates
Maiti, Bhim C.,Musgrave, Oliver C.,Skoyles, Douglas
, p. 1765 - 1771 (2007/10/03)
Methods for the conversion of 1,4,5-naphthalenetriols into the corresponding monomethoxy diacetates are described. All utilise the formation of peri-bridged intermediates.