2,2-Difluoro-2-phenylethyl phenyl sulfide

Base Information

• Chemical Name: 2,2-Difluoro-2-phenylethyl phenyl sulfide
• CAS No.: 129973-38-2
• Molecular Formula: C₁₄H₁₂F₂S
• Molecular Weight: 250.312
• Mol file: 129973-38-2.mol

Synonyms:2,2-Difluoro-2-phenylethyl phenyl sulfide

Chemical Property of 2,2-Difluoro-2-phenylethyl phenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2,2-Difluoro-2-phenylethyl phenyl sulfide

There total 1 articles about 2,2-Difluoro-2-phenylethyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

sodium thiophenolate (930-69-8) + 2-Bromo-1,1-difluoro-1-phenylethane (108661-89-8) → 2,2-Difluoro-2-phenylethyl phenyl sulfide (129973-38-2)

Guidance literature:

With N,N-dimethyl-formamide; at 25 ℃; for 2h;

DOI:10.1016/S0040-4020(01)86763-6

Reference yield: 90.0%

acetic anhydride (108-24-7) + 2,2-Difluoro-2-phenylethyl phenyl sulfide (129973-38-2) → 2,2-Difluoro-2-phenyl-1-(phenylthio)ethyl acetate (129973-45-1)

Guidance literature:

With sodium acetate; at 130 ℃; for 3h;

DOI:10.1016/S0040-4020(01)86763-6

Reference yield: 88.0%

2,2-Difluoro-2-phenylethyl phenyl sulfide (129973-38-2) → 2,2-Difluoro-2-phenylethyl phenyl sulfoxide (129973-41-7)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -40 ℃; for 3h;

DOI:10.1016/S0040-4020(01)86763-6

upstream raw materials:

sodium thiophenolate

2-Bromo-1,1-difluoro-1-phenylethane

Downstream raw materials:

2,2-Difluoro-2-phenyl-1-(phenylthio)ethyl acetate

2,2-Difluoro-2-phenylethyl phenyl sulfoxide

2,2-Difluoro-2-phenylethyl phenyl sulfone

α,α-difluoro-α-phenylacetaldehyde

Refernces