1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol

Base Information

• Chemical Name: 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol
• CAS No.: 1413282-56-0
• Molecular Formula: C₂₁H₂₀O₄
• Molecular Weight: 336.387
• Mol file: 1413282-56-0.mol

Synonyms:1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol

Chemical Property of 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol

There total 2 articles about 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1,3-bis(4-formylphenoxy)propane (3722-80-3) + acetylenemagnesium bromide (4301-14-8) → 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol (1413282-56-0)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; for 3h;

DOI:10.1039/c6ra12017b

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol (1413282-56-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 100 °C

2: tetrahydrofuran / 3 h / 0 - 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1039/c6ra12017b

Reference yield: 98.0%

1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-ol (1413282-56-0) → 1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-one (1413282-61-7)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In ethyl acetate; at 80 ℃; for 12h;

DOI:10.1039/c6ra12017b

upstream raw materials:

1,3-bis(4-formylphenoxy)propane

acetylenemagnesium bromide

4-hydroxy-benzaldehyde

Downstream raw materials:

1,1'-(4,4'-(propane-1,3-diylbis(oxy))bis(4,1-phenylene))diprop-2-yn-1-one