4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde

Base Information

• Chemical Name: 4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde
• CAS No.: 3722-80-3
• Molecular Formula: C17H16 O4
• Molecular Weight: 284.312
• DSSTox Substance ID: DTXSID20423671
• Nikkaji Number: J1.843.562D
• Wikidata: Q82235926
• ChEMBL ID: CHEMBL2380530
• Mol file: 3722-80-3.mol

Synonyms:4,4'-(propane-1,3-diylbis(oxy))dibenzaldehyde;3722-80-3;4-[3-(4-formylphenoxy)propoxy]benzaldehyde;4,4-(1,3-Propanediyl)dioxydibenzaldhyde;4,4'-[propane-1,3-diylbis(oxy)]dibenzaldehyde;1,3-Bis(4-formylphenoxy)propane;SCHEMBL5090074;CHEMBL2380530;DTXSID20423671;1,3-bis(4-formyl-phenoxy)propane;MFCD00021078;STL171294;AKOS005367828;DS-5329;4,4'-(Trimethylenebisoxy)dibenzaldehyde;3,5-DIMETHOXY-4-HYDROXYCINNAMICACID;4,4'-(Propane-1,3-diyldioxy)dibenzaldehyde;CS-0158310;4,4'-(1,3-propanediylbisoxy)bisbenzaldehyde;N10853;A848231

Chemical Property of 4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde

Chemical Property:

• PSA: 52.60000
• LogP: 3.15950
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 284.10485899
• Heavy Atom Count: 21
• Complexity: 272

Purity/Quality:

97% ^*data from raw suppliers

4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C=O)OCCCOC2=CC=C(C=C2)C=O

Technology Process of 4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde

There total 10 articles about 4,4'-(Propane-1,3-diylbis(oxy))dibenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 1,3-dibromo-propane (109-64-8) → 1,3-bis(4-formylphenoxy)propane (3722-80-3)

Guidance literature:

4-hydroxy-benzaldehyde; With potassium carbonate; In water; acetone; at 20 ℃; for 0.166667h;

1,3-dibromo-propane; In water; acetone; at 20 ℃; for 4h;

DOI:10.2174/1573406412666160811112408

Reference yield: 91.0%

3-chloropropyl p-toluenesulfonate (632-02-0) + 4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 1,3-bis(4-formylphenoxy)propane (3722-80-3) + 4-(3-chloropropoxy)benzaldehyde (82625-25-0)

Guidance literature:

With potassium carbonate; In acetonitrile; for 17.5h; Reflux; Inert atmosphere;

DOI:10.1007/s11172-017-1732-9

Reference yield: 88.1%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 1,3-bis(4-formylphenoxy)propane (3722-80-3)

Guidance literature:

With potassium carbonate; In acetonitrile; Reflux;

DOI:10.1016/j.bmcl.2017.03.060

upstream raw materials:

hydrogen cyanide

1,3-diphenoxypropane

4-hydroxy-benzaldehyde

1,3-dibromo-propane

Downstream raw materials:

4,4'-propanediyldioxy-di-benzaldehyde bis-carbamimidoylhydrazone

1,3-bis(p-carboxy-phenoxy)propane