(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

Base Information

Chemical Name:(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid
CAS No.:195060-82-3
Molecular Formula:C₂₃H₃₂O₂
Molecular Weight:340.506
Hs Code.:

Synonyms:(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

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Chemical Property of (R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

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Technology Process of (R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

There total 4 articles about (R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 90878-19-6
phenethylmagnesium chloride

: 195060-78-7
C₁₈H₃₀O₂Si

: 195060-82-3
(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

Guidance literature:: With copper(l) iodide; chloro-trimethyl-silane; In tetrahydrofuran; at -78 ℃;
DOI:10.1016/S0040-4039(97)01428-7

Reference yield:

: 90878-19-6
phenethylmagnesium chloride

: 195060-79-8
C₂₁H₃₆O₂Si

: (S)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

: 195060-82-3
(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

Guidance literature:: With copper(l) iodide; In tetrahydrofuran; at -78 ℃; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(97)01428-7

Reference yield:

: 90878-19-6
phenethylmagnesium chloride

: 195060-80-1
C₂₄H₄₂O₂Si

: (S)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

: 195060-82-3
(R)-2-((1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-naphthalen-1-yl)-5-phenyl-pentanoic acid

Guidance literature:: With copper(l) iodide; chloro-trimethyl-silane; In tetrahydrofuran; at -78 ℃; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(97)01428-7