1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

Base Information

Chemical Name:1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide
CAS No.:70977-92-3
Molecular Formula:C₂₁H₂₃N₅O₄
Molecular Weight:409.445
Hs Code.:

1-(4-methoxy-benzyl)-1<i>H</i>-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

Synonyms:1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

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Chemical Property of 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

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Technology Process of 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

There total 5 articles about 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70978-42-6
2-hydroxy-5-methyl-3-nitro-isobutyrophenone

: 70977-92-3
1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / H₂ / 5percent Pd/C / ethanol

2: pyridine / CH₂Cl₂ / 1 h / 20 °C

With pyridine; hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm00154a019

Reference yield:

: 64207-03-0
1-(2-hydroxy-5-methylphenyl)-2-methylpropan-1-one

: 70977-92-3
1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 2-hydroxy-3-isobutyryl-5-methyl-anilide

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / conc. HNO₃, conc. H₂SO₄ / -20 °C

2: 89 percent / H₂ / 5percent Pd/C / ethanol

3: pyridine / CH₂Cl₂ / 1 h / 20 °C

With pyridine; sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm00154a019