1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one

Base Information

• Chemical Name: 1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one
• CAS No.: 36715-57-8
• Molecular Formula: C₁₄H₁₂BrNO
• Molecular Weight: 290.159
• Mol file: 36715-57-8.mol

Synonyms:1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one

Chemical Property of 1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one

There total 1 articles about 1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.19%

N-methylpyrrole aldehyde (1192-58-1) + para-bromoacetophenone (99-90-1) → 1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one (36715-57-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃; for 3.5h;

DOI:10.1016/j.molstruc.2017.03.090

Reference yield:

1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one (36715-57-8) → C18H12BrN3O2 (1312797-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / Reflux

2: 3 h / Reflux

With ammonium acetate; In ethanol;

DOI:10.1007/s00044-010-9469-0

Reference yield:

1-(4-bromophenyl)-3-(1-methyl-1H-pyrrol-3-yl)prop-2-en-1-one (36715-57-8) → C17H11BrN4O2

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / Reflux

2: sodium nitrite / water; acetic acid / 4 h / Cooling with ice

With ammonium acetate; sodium nitrite; In ethanol; water; acetic acid;

DOI:10.1007/s00044-010-9469-0

upstream raw materials:

N-methylpyrrole aldehyde

para-bromoacetophenone

Downstream raw materials:

C₁₈H₁₂BrN₃O₂

C₂₄H₁₇BrN₄OS

C₂₄H₁₆BrFN₄OS

C₁₉H₁₆BrN₃O