2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester

Base Information

• Chemical Name: 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester
• CAS No.: 27144-26-9
• Molecular Formula: C₂₈H₃₆N₂O₈
• Molecular Weight: 528.602

Synonyms:2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester

Chemical Property of 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester

There total 3 articles about 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-diisopropylphenol (2078-54-8) → 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester (27144-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) KOH, DMSO, (ii) /BRN= 505943/, SnCl₄, CS₂

2: (i) NaOEt, EtOH, (ii) /BRN= 2305318/

DOI:10.1021/jm00297a007

Reference yield:

4-chlorobenzonitrile (100-00-5) → 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester (27144-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) KOH, DMSO, (ii) /BRN= 505943/, SnCl₄, CS₂

2: (i) NaOEt, EtOH, (ii) /BRN= 2305318/

DOI:10.1021/jm00297a007

Reference yield:

5-Chloromethyl-1,3-diisopropyl-2-(4-nitro-phenoxy)-benzene (27144-21-4) + 2-acetylaminomalonic acid diethyl ester (1068-90-2) → 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester (27144-26-9)

Guidance literature:

Multistep reaction; (i) NaOEt, EtOH, (ii) /BRN= 2305318/;

DOI:10.1021/jm00297a007

upstream raw materials:

5-Chloromethyl-1,3-diisopropyl-2-(4-nitro-phenoxy)-benzene

2-acetylaminomalonic acid diethyl ester

2,6-diisopropylphenol

4-chlorobenzonitrile

Downstream raw materials:

3,5-Diisopropyl-3'-iod-DL-thyronin

2-Amino-3-[4-(3-bromo-4-hydroxy-phenoxy)-3,5-diisopropyl-phenyl]-propionic acid

2-Amino-3-[4-(4-amino-phenoxy)-3,5-diisopropyl-phenyl]-propionic acid

2-Acetylamino-2-[4-(4-amino-phenoxy)-3,5-diisopropyl-benzyl]-malonic acid diethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 27144-26-9 2-Acetylamino-2-[3,5-diisopropyl-4-(4-nitro-phenoxy)-benzyl]-malonic acid diethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send