Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate

Base Information Edit

Chemical Name:Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate
CAS No.:103457-73-4
Molecular Formula:C₂₃H₁₇NO₄
Molecular Weight:371.392
Hs Code.:
DSSTox Substance ID:DTXSID601133206
Mol file:103457-73-4.mol

Synonyms:DTXSID601133206;Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate;103457-73-4

Suppliers and Price of Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate Edit

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:371.11575802
Heavy Atom Count:28
Complexity:682

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1C(=NOC12C3=CC=CC4=C3C(=CC=C4)C2=O)C5=CC=CC=C5

Technology Process of Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate

There total 2 articles about Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1(2H),5'(4'H)-isoxazole]-4'-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 22561-90-6
Ethyl Z-(1,2-dihydro-2-oxo-1-acenaphthylenylidene)acetate

: 698-16-8
benzohydroximoyl chloride

: 103457-73-4
Ethyl 2-oxo-3'-phenylspiro-4'-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; for 3h; Heating;

Reference yield:

: 103457-76-7
Ethyl (3'-phenylspirodioxazole>-2-ylidene)acetate

: 698-16-8
benzohydroximoyl chloride

: 103457-73-4
Ethyl 2-oxo-3'-phenylspiro-4'-carboxylate

: 103457-78-9
Ethyl 2-hydroxy-3'-phenylspiro-4'-carboxylate

Guidance literature:: With boric acid; triethylamine; palladium on activated charcoal; Yield given. Multistep reaction. Yields of byproduct given; 1.) CH₂Cl₂, 4h, reflux 2.) CH₃OH, H₂O, ethyl acetate, 28h;