33831-72-0

Basic information

• Product Name: 3-AMINO-3-PHENYL-2-PROPENOIC ACID ETHYL ESTER
• Synonyms: 3-AMINO-3-PHENYL-2-PROPENOIC ACID ETHYL ESTER
• CAS NO: 33831-72-0
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.229
• Mol File: 33831-72-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 342.9°Cat760mmHg
• Flash Point: 189.7°C
• Appearance: /
• Density: 1.099g/cm³
• Vapor Pressure: 7.28E-05mmHg at 25°C
• Refractive Index: 1.549
• PKA: 3.93±0.70(Predicted)
• CAS DataBase Reference: 3-AMINO-3-PHENYL-2-PROPENOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-PHENYL-2-PROPENOIC ACID ETHYL ESTER(33831-72-0)
• EPA Substance Registry System: 3-AMINO-3-PHENYL-2-PROPENOIC ACID ETHYL ESTER(33831-72-0)

Safety Data

• Hazardous Substances Data: 33831-72-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13NO2/c1-2-14-11(13)8-10(12)9-6-4-3-5-7-9/h3-8H,2,12H2,1H3

Upstream product

• 64-17-5 ethanol 
• 57-13-6 urea 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 105-56-6 ethyl 2-cyanoacetate 
• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 42970-55-8 3-phenyl-2H-azirine-2-carboxaldehyde 
• 105-36-2 ethyl bromoacetate 
• 100-47-0 benzonitrile 
• 98-86-2 acetophenone 
• 5873-90-5 methyl benzimidate hydrochloride 
• 698-16-8 benzohydroximoyl chloride 
• 7664-41-7 ammonia 
• 103457-73-4 Ethyl 2-oxo-3'-phenylspiro-4'-carboxylate 
• 141-78-6 ethyl acetate 

Downstream Products

• 4996-29-6 6-Phenyl-2,3-trimethylene-3,4-dihydropyrimidin-4-one 
• 145013-58-7 5-Ethoxycarbonyl-4-methyl-6-phenyl-3,4-dihydro-2(1H)-pyridon 
• 33912-78-6 ethyl (E)-3-(acetylamino)-3-phenyl-2-propenoate 
• 33912-78-6 ethyl (Z)-β-phenyl-β-(acetylamino)acrylate 
• 1400358-41-9 C₂₁H₁₈BrNO₃ 
• 1400358-43-1 C₂₂H₂₁NO₃ 
• 143615-00-3 (2R,3S)-3-amino-3-phenyl-2-hydroxypropionic acid ethyl ester 
• 854254-67-4 ethyl 6-phenyl-[1,3]dioxolo[4,5-g]quinoline-7-carboxylate 
• 597585-09-6 ethyl 6,7-dimethoxy-2-phenyl-3-quinolinecarboxylate 
• 30160-12-4 2-phenylquinoline-3-carboxylic acid ethyl ester 
• 1334529-04-2 (R)-ethyl 6-oxo-2,4-diphenyl-1,4,5,6-tetrahydropyridine-3-carboxylate 

Relevant articles and documents

Carbene-Catalyzed [4 + 2] Annulation of 2 H-Azirine-2-carboxaldehydes with Ketones via Azolium Aza-Dienolate Intermediate

A new carbene-catalyzed [4 + 2] annulation of 2H-azirine-2-carbaldehydes with ketones was developed, thus providing the 2,3-dihydro-6H-1,3-oxazin-6-one core structures with broad scope and good to excellent yields. Notably, the azolium aza-dienolates gene

Electrochemical Oxidative Cyclization: Synthesis of Polysubstituted Pyrrole from Enamines

A conceptually novel method for the preparation of pyrrole is described by electrochemical-oxidation-induced intermolecular annulation via enamines. In a simple undivided cell, based on a sodium acetate-facilitated, polysubstituted pyrrole derivations has been facilely synthesized under external oxidant-free condition. This electrosynthetic approach providing an environmentally benign protocol for C?C bond cross-coupling and oxidative annulation, which features unparalleled broad scope of substrates and practicality.

Divergent Synthesis of Multisubstituted Unsymmetric Pyrroles and Pyrrolin-4-ones from Enamino Esters via Copper-Catalyzed Aerobic Dimerization

A facile synthetic method to access multisubstituted unsymmetric pyrrole and pyrrolin-4-one derivatives is disclosed. In the presence of Cu(OAc)2 and KOAc, substituted pyrrole derivatives are produced in good yields (up to 93 %) through oxidative cyclization of enamino esters. Meanwhile, using CuCl2 and TFA (trifluoroacetic acid), pyrrolin-4-one derivatives are obtained in excellent yields (up to 94 %) through 1,2-aryl migration. A wide range of functional groups have been tolerated, and a reliable method for the synthesis of valuable multisubstituted pyrroles and pyrrolin-4-ones has been developed.