C₇₇H₈₆O₁₃Si

Base Information

• Chemical Name: C₇₇H₈₆O₁₃Si
• CAS No.: 324740-36-5
• Molecular Formula: C₇₇H₈₆O₁₃Si
• Molecular Weight: 1247.61
• Mol file: 324740-36-5.mol

Synonyms:C₇₇H₈₆O₁₃Si

Chemical Property of C₇₇H₈₆O₁₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₇H₈₆O₁₃Si

There total 7 articles about C₇₇H₈₆O₁₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate (149707-75-5) + Acetic acid (2R,6S)-6-[(3S,8S,9S,10R,13S,14S,17R)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-16-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxo-heptyl ester (324740-33-2) → C77H86O13Si (324740-36-5)

Guidance literature:

Acetic acid (2R,6S)-6-[(3S,8S,9S,10R,13S,14S,17R)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-16-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxo-heptyl ester; With potassium carbonate; In tetrahydrofuran; methanol; at 20 ℃;

2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 - 20 ℃;

DOI:10.1016/S0040-4039(00)01889-X

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C77H86O13Si (324740-36-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 99 percent / imidazole / dimethylformamide / 20 °C

2.1: Br₂ / CHCl₃ / 0 - 20 °C

3.1: KHSO₅; NaHCO₃ / acetone; CH₂Cl₂ / 20 °C

4.1: 35 percent / acetic acid

5.1: Zn; NH₄Cl / ethanol / Heating

6.1: K₂CO₃ / tetrahydrofuran; methanol / 20 °C

6.2: TMSOTf / CH₂Cl₂ / -78 - 20 °C

With 1H-imidazole; potassium peroxomonosulfate; bromine; sodium hydrogencarbonate; potassium carbonate; ammonium chloride; zinc; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; acetic acid; N,N-dimethyl-formamide; acetone;

DOI:10.1016/S0040-4039(00)01889-X

Reference yield:

3-O-(tert-butyldiphenylsilyl)diosgenin (324740-29-6) → C77H86O13Si (324740-36-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: Br₂ / CHCl₃ / 0 - 20 °C

2.1: KHSO₅; NaHCO₃ / acetone; CH₂Cl₂ / 20 °C

3.1: 35 percent / acetic acid

4.1: Zn; NH₄Cl / ethanol / Heating

5.1: K₂CO₃ / tetrahydrofuran; methanol / 20 °C

5.2: TMSOTf / CH₂Cl₂ / -78 - 20 °C

With potassium peroxomonosulfate; bromine; sodium hydrogencarbonate; potassium carbonate; ammonium chloride; zinc; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; acetic acid; acetone;

DOI:10.1016/S0040-4039(00)01889-X

upstream raw materials:

2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate

Acetic acid (2R,6S)-6-[(3S,8S,9S,10R,13S,14S,17R)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-16-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-5-oxo-heptyl ester

tert-butylchlorodiphenylsilane

3-O-(tert-butyldiphenylsilyl)diosgenin

Downstream raw materials:

C₆₁H₆₈O₁₃