cyclopropyl ketone

Base Information

Chemical Name:cyclopropyl ketone
CAS No.:1425044-26-3
Molecular Formula:C₂₅H₂₂ClN₅O₂
Molecular Weight:459.935
Hs Code.:

Synonyms:cyclopropyl ketone

Suppliers and Price of cyclopropyl ketone

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Chemical Property of cyclopropyl ketone

Chemical Property:

Purity/Quality:

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Technology Process of cyclopropyl ketone

There total 7 articles about cyclopropyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1425045-79-9
C₃₇H₄₁ClN₆O₇

: 23719-80-4
cyclopropylmagnesium bromide

: 1425044-26-3
cyclopropyl ketone

Guidance literature:: C₃₇H₄₁ClN₆O₇; cyclopropylmagnesium bromide; With hydrogenchloride; trifluoroacetic acid; In tetrahydrofuran; at 0 ℃; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; Cooling;

With trifluoroacetic acid; at 20 ℃;

Reference yield:

: 1386861-46-6
2-chloro-6-methyl-N-phenylbenzamide

: 1425044-26-3
cyclopropyl ketone

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -30 - -10 °C / Inert atmosphere

1.2: 2 h / -30 - -10 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 16 h / 120 °C / Sealed tube

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) iodide / N,N-dimethyl-formamide / 16 h / 80 °C

4.1: dmap / tetrahydrofuran / Reflux

5.1: hydrogenchloride; trifluoroacetic acid / tetrahydrofuran / 0 °C / Reflux

5.2: Cooling

5.3: 20 °C

With hydrogenchloride; dmap; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; hexane; N,N-dimethyl-formamide;

Reference yield:

: 62-53-3
aniline

: 1425044-26-3
cyclopropyl ketone

Guidance literature:: Multi-step reaction with 6 steps

1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C

1.2: 2 h / 20 - 40 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -30 - -10 °C / Inert atmosphere

2.2: 2 h / -30 - -10 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 16 h / 120 °C / Sealed tube

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(l) iodide / N,N-dimethyl-formamide / 16 h / 80 °C

5.1: dmap / tetrahydrofuran / Reflux

6.1: hydrogenchloride; trifluoroacetic acid / tetrahydrofuran / 0 °C / Reflux

6.2: Cooling

6.3: 20 °C

With hydrogenchloride; dmap; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; trifluoroacetic acid; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; hexane; dichloromethane; N,N-dimethyl-formamide;