2-(2-Chloro-5-methoxyphenyl)acetic acid

Base Information

Chemical Name:2-(2-Chloro-5-methoxyphenyl)acetic acid
CAS No.:91367-10-1
Molecular Formula:C₉H₉ClO₃
Molecular Weight:200.622
Hs Code.:
DSSTox Substance ID:DTXSID301290803

Synonyms:2-(2-chloro-5-methoxyphenyl)acetic acid;91367-10-1;2-(2-chloro-5-methoxyphenyl)aceticacid;(2-chloro-5-methoxy-phenyl)-acetic acid;(2-chloro-5-methoxyphenyl)acetic acid;SCHEMBL473974;NLBOKHCTHYDHRG-UHFFFAOYSA-N;DTXSID301290803;2-Chloro-5-methoxybenzeneacetic acid;MFCD09925191;2-Chloro-5-methoxy-benzeneacetic acid;AKOS015948397;NS-02048;2-(2-chloro-5-methoxy-phenyl)acetic acid;EN300-719634;F85843;Z1269186781

Suppliers and Price of 2-(2-Chloro-5-methoxyphenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-chloro-5-methoxyphenyl)aceticAcid
100mg
$ 330.00

TRC
2-(2-chloro-5-methoxyphenyl)aceticAcid
50mg
$ 220.00

Total 3 raw suppliers

Chemical Property of 2-(2-Chloro-5-methoxyphenyl)acetic acid

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.0240218
Heavy Atom Count:13
Complexity:184

Purity/Quality:: 2-(2-chloro-5-methoxyphenyl)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)Cl)CC(=O)O

Technology Process of 2-(2-Chloro-5-methoxyphenyl)acetic acid

There total 8 articles about 2-(2-Chloro-5-methoxyphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1798-09-0
m-methoxyphenylacetic acid

: 91367-10-1
2-(2-chloro-5-methoxy-phenyl)acetic acid

Guidance literature:: With N-chloro-succinimide; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 24h;

Reference yield:

: 5020-41-7
2-(3-methoxyphenyl)-ethanol

: 1798-09-0
m-methoxyphenylacetic acid

: 91367-10-1
2-(2-chloro-5-methoxy-phenyl)acetic acid

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; Yields of byproduct given;
DOI:10.1021/jo982143y

Reference yield:

: 3771-13-9
2-(bromomethyl)-1-chloro-4-methoxybenzene

: 91367-10-1
2-(2-chloro-5-methoxy-phenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O / dimethylformamide

2: H₂SO₄, aq. AcOH

With sulfuric acid; water; acetic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jo01059a110