Technology Process of (2,6-diisopropylphenyl)acetylene
There total 8 articles about (2,6-diisopropylphenyl)acetylene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
trimethylsilylacetylene; 2-iodo-1,3-diisopropylbenzene;
With
diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide;
In
toluene;
at 20 - 65 ℃;
for 13h;
Inert atmosphere;
With
methanol; potassium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: BrCCl3, isopentyl nitrite / 1,2-dimethoxy-ethane / 14 h / 75 °C
2: 1.) Mg, iodine, 1,2-dibromoethane / 1.) ether, reflux, 15 h, 2.) ether, reflux, 2 h
3: 48 percent / KHSO4 / 180 °C / 40 Torr
4: 72 percent / Br2 / CHCl3 / 0.08 h
5: 32 percent / KOH / ethanol / 0.17 h / 50 °C
6: 30percent NaNH2 / toluene; tetrahydrofuran / 10 h / Heating
With
potassium hydroxide; potassium hydrogensulfate; Bromotrichloromethane; bromine; iodine; sodium amide; magnesium; ethylene dibromide; isopentyl nitrite;
In
tetrahydrofuran; 1,2-dimethoxyethane; ethanol; chloroform; toluene;
- Guidance literature:
-
With
sodium amide;
In
tetrahydrofuran; toluene;
for 10h;
Heating;
