2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester

Base Information

• Chemical Name: 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester
• CAS No.: 191725-30-1
• Molecular Formula: C₁₂H₁₄N₂O₆
• Molecular Weight: 282.253
• Mol file: 191725-30-1.mol

Synonyms:2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester

Chemical Property of 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester

There total 2 articles about 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

N-benzoyl-α-methylserine methyl ester (191725-34-5) → 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester (191725-30-1)

Guidance literature:

With nitric acid; acetic anhydride; at 0 ℃; for 0.0833333h;

Reference yield:

benzoyl chloride (98-88-4) → 2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester (191725-30-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.94 g / NaHCO₃ / ethyl acetate; H₂O / 4 h / Ambient temperature

2: 72 percent / HNO₃, acetic anhydride / 0.08 h / 0 °C

With nitric acid; acetic anhydride; sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield: 88.0%

2-Benzoylamino-2-methyl-3-nitrooxy-propionic acid methyl ester (191725-30-1) → methyl N-benzoylalaninate (7244-67-9,38767-73-6)

Guidance literature:

With ethylbenzene; tri-n-butyl-tin hydride; In benzene-d6; at 40 ℃; for 2h; Irradiation;

upstream raw materials:

N-benzoyl-α-methylserine methyl ester

benzoyl chloride

Downstream raw materials:

methyl N-benzoylalaninate