(S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester

Base Information

• Chemical Name: (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester
• CAS No.: 103127-55-5
• Molecular Formula: C₁₄H₂₅NO₃
• Molecular Weight: 255.357
• Mol file: 103127-55-5.mol

Synonyms:(S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester

Chemical Property of (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester

There total 11 articles about (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(S)-2-cyclohexyl-1-(hydroxymethyl)ethyl]carbamic acid,1,1-dimethylethyl ester (194342-34-2) → (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester (103127-55-5)

Guidance literature:

With pyridine-SO₃ complex; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; at -20 - 20 ℃; for 4h;

Reference yield:

[(S)-2-cyclohexyl-1-(hydroxymethyl)ethyl]carbamic acid,1,1-dimethylethyl ester (194342-34-2) → (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester (103127-55-5)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; sodium hydrogencarbonate; tert-butyl alcohol;

Reference yield:

2-t-butoxycarbonylamino-3-cyclohexylpropionic acid methyl ester → (S)-(2-cyclohexyl-1-formylethyl)carbamic acid,1,1-dimethylethyl ester (103127-55-5)

Guidance literature:

With diisobutylaluminium hydride; In methanol; hexane; toluene;

upstream raw materials:

ethyl N-(diphenylmethylene)-DL-cyclohexylalaninate

N-tert-butoxycarbonyl-cyclohexylalanine

ethyl 2-amino-3-cyclohexylpropionate

Dess-Martin periodane

Downstream raw materials:

3-endo-[8-(2-amino-3-cyclohexylpropyl)-8-aza-bicyclo[3.2.1]oct-3-yl]phenol

(2-carbamoyl-1-cyclohexylmethyl-2-hydroxy-ethyl)-carbamic acid tert-butyl ester

(2-cyano-1-cyclohexylmethyl-2-hydroxy-ethyl)-carbamic acid tert-butyl ester