2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Base Information

Chemical Name:2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole
CAS No.:42076-30-2
Molecular Formula:C₁₆H₁₂N₂
Molecular Weight:232.285
Hs Code.:
DSSTox Substance ID:DTXSID401260253

Synonyms:42076-30-2;2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole;1H-Benzimidazole, 2-phenyl-1-(2-propyn-1-yl)-;2-phenyl-1-prop-2-ynylbenzimidazole;DTXSID401260253;HMS1631B05;STK866124;AKOS000587271;2-phenyl-1-prop-2-ynyl-1H-benzimidazole;2-Phenyl-1-(2-propyn-1-yl)-1H-benzimidazole;2-phenyl-1-(prop-2-yn-1-yl)-1h-benzoimidazole;2-phenyl-1-(prop-2-yn-1-yl)-1H-benzo[d]imidazole;Z57822409;F3000-0042

Suppliers and Price of 2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:232.100048391
Heavy Atom Count:18
Complexity:323

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CCN1C2=CC=CC=C2N=C1C3=CC=CC=C3

Technology Process of 2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

There total 7 articles about 2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 106-96-7
propargyl bromide

: 716-79-0
2-phenyl-1H-benzoimidazole

: 42076-30-2
2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Guidance literature:: With potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 50 ℃; for 10h; Inert atmosphere; Sonication;
DOI:10.1134/S0012500812110018

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 42076-30-2
2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1-dodecylimidazolium hydrogensulfonate; oxygen / ethanol / 5 h / 20 °C

2: potassium hydroxide / acetonitrile / 3 h / 20 °C

With 1-dodecylimidazolium hydrogensulfonate; oxygen; potassium hydroxide; In ethanol; acetonitrile;
DOI:10.1016/j.tet.2019.05.014

Reference yield:

: 100-52-7
benzaldehyde

: 42076-30-2
2-phenyl-1-(prop-2-yn-1-yl)-1H-benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1-dodecylimidazolium hydrogensulfonate; oxygen / ethanol / 5 h / 20 °C

2: potassium hydroxide / acetonitrile / 3 h / 20 °C

With 1-dodecylimidazolium hydrogensulfonate; oxygen; potassium hydroxide; In ethanol; acetonitrile;
DOI:10.1016/j.tet.2019.05.014