Piperazinone, 3-(2-thienyl)- (9CI)

Base Information

• Chemical Name: Piperazinone, 3-(2-thienyl)- (9CI)
• CAS No.: 86696-86-8
• Molecular Formula: C8H10N2OS
• Molecular Weight: 182.246
• Mol file: 86696-86-8.mol

Synonyms:Quinoxaline,2-chloro-3-(2-thienyl);3-(2-thienyl)-2-chloroquinoxaline;3-(2-Thienyl)-tetrahydro-pyrazin-2-on;3-(2-thienyl)-piperazin-2-one;2-chloro-3-(2-thienyl)quinoxaline;2-chloro-3-thienylquinoxaline;2-chloro-3-(thiophen-2-yl)quinoxaline;3-(thien-2-yl)-piperazin-2-one;

Chemical Property of Piperazinone, 3-(2-thienyl)- (9CI)

Chemical Property:

• Vapor Pressure: 3.27E-07mmHg at 25°C
• Boiling Point: 418.5°C at 760 mmHg
• Flash Point: 206.9°C
• PSA: 72.86000
• Density: 1.225
• LogP: 1.11330

Purity/Quality:

99% ^*data from raw suppliers

3-(thiophen-2-yl)piperazin-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Piperazinone, 3-(2-thienyl)- (9CI)

There total 1 articles about Piperazinone, 3-(2-thienyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(thien-2-yl)-5,6-dihydro-(1H)-pyrazin-2-one (85606-87-7) → Tenilsetam (86696-86-8,85606-97-9)

Guidance literature:

Reference yield: 79.0%

Tenilsetam (86696-86-8,85606-97-9) → 2--2-(2-thienyl)-essigsaeuredihydrochlorid

Guidance literature:

With hydrogenchloride; for 15h; Ambient temperature;

Reference yield: 73.0%

Tenilsetam (86696-86-8,85606-97-9) + 2,6-dichlorophenylisocyanate (39920-37-1) → 4-(2,6-Dichlorphenylaminocarbonyl)-3-(2-thienyl)-tetrahydropyrazin-2-on

Guidance literature:

In toluene; for 1h; Ambient temperature;

upstream raw materials:

3-(thien-2-yl)-5,6-dihydro-(1H)-pyrazin-2-one

Downstream raw materials:

[2-(2,6-Dichloro-phenylamino)-4,5-dihydro-imidazol-1-yl]-thiophen-2-yl-acetic acid

Refernces