(1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane

Base Information

• Chemical Name: (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane
• CAS No.: 157116-99-9
• Molecular Formula: C₁₅H₁₈O₅
• Molecular Weight: 278.305

Synonyms:(1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane

Chemical Property of (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane

There total 5 articles about (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-O-benzyl-1,6:2,3-dianhydro-β-D-mannopyranose (33208-47-8) → (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.02,4]nonane (157116-99-9)

Guidance literature:

Multi-step reaction with 7 steps

1: diethyl ether / Ambient temperature

2: Et₃N / DMAP / CH₂Cl₂ / Ambient temperature

4: DEAD-Ph₃P / CH₂Cl₂ / Ambient temperature

5: H₂ / Pd/C / methanol

6: Et₃N / CH₂Cl₂ / -10 °C

7: MeONa / methanol / Ambient temperature

With hydrogen; sodium methylate; triethylamine; triphenylphosphine; diethylazodicarboxylate; dmap; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane;

DOI:10.1016/S0040-4039(00)75797-2

Reference yield:

Acetic acid (1R,2S,3R,4R,5R)-4-allyl-2-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl ester (157116-97-7) → (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.02,4]nonane (157116-99-9)

Guidance literature:

Multi-step reaction with 5 steps

2: DEAD-Ph₃P / CH₂Cl₂ / Ambient temperature

3: H₂ / Pd/C / methanol

4: Et₃N / CH₂Cl₂ / -10 °C

5: MeONa / methanol / Ambient temperature

With hydrogen; sodium methylate; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1016/S0040-4039(00)75797-2

Reference yield:

Acetic acid (1R,2S,3R,4R,5R)-2-benzyloxy-4-[2-(4-methoxy-phenoxy)-ethyl]-6,8-dioxa-bicyclo[3.2.1]oct-3-yl ester (157116-98-8) → (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.02,4]nonane (157116-99-9)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd/C / methanol

2: Et₃N / CH₂Cl₂ / -10 °C

3: MeONa / methanol / Ambient temperature

With hydrogen; sodium methylate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1016/S0040-4039(00)75797-2

upstream raw materials:

4-O-benzyl-1,6:2,3-dianhydro-β-D-mannopyranose

Acetic acid (1R,2S,3R,4R,5R)-4-allyl-2-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl ester

Acetic acid (1R,2S,3R,4R,5R)-2-benzyloxy-4-[2-(4-methoxy-phenoxy)-ethyl]-6,8-dioxa-bicyclo[3.2.1]oct-3-yl ester

Downstream raw materials:

(1S,2S,3S,4R,5R)-4-[2-(4-Methoxy-phenoxy)-ethyl]-2-propyl-6,8-dioxa-bicyclo[3.2.1]octan-3-ol

2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-[2-(4-methoxy-phenoxy)-ethyl]-3-methyl-6-propyl-cyclohexylmethyl ester

2,2-Dimethyl-butyric acid (1S,2R,5S,6S)-6-[2-(4-methoxy-phenoxy)-ethyl]-5-methyl-2-propyl-cyclohex-3-enylmethyl ester

2,2-Dimethyl-butyric acid (1R,2S,6S)-2-[2-(4-methoxy-phenoxy)-ethyl]-5-oxo-6-propyl-cyclohex-3-enylmethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 157116-99-9 (1R,2R,4R,5R,6R)-5-[2-(4-Methoxy-phenoxy)-ethyl]-3,7,9-trioxa-tricyclo[4.2.1.0^2,4]nonane

Send

Send

Metric Ton KG G Pound L ML

Send

Send