2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

Base Information

Chemical Name:2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate
CAS No.:1286182-76-0
Molecular Formula:C₂H₄O₂*C₁₂H₁₅N₃O₂
Molecular Weight:293.323
Hs Code.:

Synonyms:2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

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Chemical Property of 2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

Chemical Property:

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Technology Process of 2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

There total 3 articles about 2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1286182-73-7
3-[5-(1-hydroxy-1-methylethyl)-[1,2,4]oxadiazol-3-yl]benzaldehyde oxime

: 1286182-76-0
2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

Guidance literature:: With acetic acid; zinc; at 22 - 26 ℃; Inert atmosphere;

Reference yield:

: 24964-64-5
3-Cyanobenzaldehyde

: 1286182-76-0
2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydroxylamine hydrochloride / ethanol; water / 20 - 25 °C / Inert atmosphere

1.2: 20 - 78 °C

2.1: 1-methyl-pyrrolidin-2-one / 22 - 27 °C / Inert atmosphere

2.2: 25 - 30 °C

3.1: zinc; acetic acid / 22 - 26 °C / Inert atmosphere

With hydroxylamine hydrochloride; acetic acid; zinc; In 1-methyl-pyrrolidin-2-one; ethanol; water;

Reference yield:

: 1256486-34-6
N-hydroxy-3-(hydroxyiminomethyl)benzamidine

: 1286182-76-0
2-[3-(3-aminomethylphenyl)-[1,2,4]-oxadiazol-5-yl]-propan-2-ol acetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-methyl-pyrrolidin-2-one / 22 - 27 °C / Inert atmosphere

1.2: 25 - 30 °C

2.1: zinc; acetic acid / 22 - 26 °C / Inert atmosphere

With acetic acid; zinc; In 1-methyl-pyrrolidin-2-one;