(2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate

Base Information

Chemical Name:(2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate
CAS No.:196707-32-1
Molecular Formula:C13H15FNO4-
Molecular Weight:269.273
Hs Code.:29224985
DSSTox Substance ID:DTXSID60426545
Wikidata:Q82239435
Mol file:196707-32-1.mol

Synonyms:(2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate;(2R)-2-(4-fluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate;DTXSID60426545

Suppliers and Price of (2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid 95+%
1g
$ 421.00

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid 95+%
5g
$ 1532.00

American Custom Chemicals Corporation
(R)-N-BOC-4-FLUORO PHENYLGLYCINE 95.00%
1G
$ 664.78

American Custom Chemicals Corporation
(R)-N-BOC-4-FLUORO PHENYLGLYCINE 95.00%
5G
$ 3467.31

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid
5g
$ 1605.76

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid
1g
$ 446.25

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid
250mg
$ 183.60

Activate Scientific
(R)-N-Boc-4-fluorophenylglycine 95% ee
1 g
$ 205.00

Acrotein
Boc-(R)-2-amino-2-(4-fluorophenyl)aceticacid 97%
1g
$ 137.50

Total 11 raw suppliers

Chemical Property of (2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate

Chemical Property:

Vapor Pressure:2.1E-07mmHg at 25°C
Melting Point:85.7 °C
Boiling Point:408.4°Cat760mmHg
PKA:3.47±0.10(Predicted)
Flash Point:200.8°C
PSA：75.63000
Density:g/cm³
LogP:2.86700
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:268.09851112
Heavy Atom Count:19
Complexity:327

Purity/Quality:

98%min ^*data from raw suppliers

(R)-2-((tert-Butoxycarbonyl)amino)-2-(4-fluorophenyl)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C1=CC=C(C=C1)F)C(=O)[O-]
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](C1=CC=C(C=C1)F)C(=O)[O-]

Technology Process of (2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate

There total 6 articles about (2R)-[(tert-Butoxycarbonyl)amino](4-fluorophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 351-95-1
N-(4-fluoro-phenyl)-glycine

: 196707-32-1
(2R)-2-{[(tert-butoxy)carbonyl]amino}-2-(4-fluorophenyl)acetic acid

Guidance literature:: With sodium hydrogencarbonate; In water; tert-butyl alcohol; at 20 ℃;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 93939-74-3
(R)-2-(4-fluorophenyl)glycine

: 196707-32-1
(2R)-2-{[(tert-butoxy)carbonyl]amino}-2-(4-fluorophenyl)acetic acid

Guidance literature:: (R)-2-(4-fluorophenyl)glycine; With sodium hydrogencarbonate; In water; for 0.5h;

di-tert-butyl dicarbonate; In water; tert-butyl alcohol; at 20 ℃;

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 196707-30-9
N-(trimethylsilyl)-N-(tert-butyloxycarbonyl)-4-fluorobenzylamine

: 142186-36-5
(S)-2-((tert-butoxycarbonyl)amino)-2-(4-fluorophenyl)acetic acid

: 196707-32-1
(2R)-2-{[(tert-butoxy)carbonyl]amino}-2-(4-fluorophenyl)acetic acid

Guidance literature:: With sec.-butyllithium; (-)-sparteine; In hexane; at -78 ℃; for 0.333333h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0040-4039(97)01515-3