Technology Process of C26H34F3NO2Si
There total 4 articles about C26H34F3NO2Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C21H22F3NO2;
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane;
at 20 ℃;
for 0.166667h;
Inert atmosphere;
2-(Trimethylsilyl)ethanol;
In
dichloromethane;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1016/j.bmc.2012.08.034
DOI:10.1016/j.bmc.2012.08.034
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium iodide / acetonitrile / 0.25 h / 20 °C / Inert atmosphere
2.1: lithium hydroxide monohydrate / methanol; tetrahydrofuran; water
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
3.2: 1 h / 20 °C / Inert atmosphere
With
dmap; lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; potassium iodide;
In
tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1016/j.bmc.2012.08.034
DOI:10.1016/j.bmc.2012.08.034
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hydroxide monohydrate / methanol; tetrahydrofuran; water
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
With
dmap; lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1016/j.bmc.2012.08.034
DOI:10.1016/j.bmc.2012.08.034
