N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

Base Information

Chemical Name:N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide
CAS No.:1070794-74-9
Molecular Formula:C₂₅H₃₇N₃O₄S₂
Molecular Weight:507.718
Hs Code.:

Synonyms:N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

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Chemical Property of N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

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Technology Process of N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

There total 3 articles about N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 436151-85-8
2-amino-4-(4′-cyanophenyl)thiazole

: 1070795-76-4
C₁₅H₂₉NO₄S

: 1070794-74-9
N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

Guidance literature:: With pyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; Heating / reflux;

Reference yield:

: BrH*C₉H₆BrNO

: 1070794-74-9
N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Heating / reflux

2: pyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / Heating / reflux

With pyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 1443-80-7
4-cyanophenyl methyl ketone

: 1070794-74-9
N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-(1-octylsulfonylpiperidin-4-yl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen bromide; bromine; acetic acid

2: ethanol / Heating / reflux

3: pyridine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / Heating / reflux

With pyridine; hydrogen bromide; bromine; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; N,N-dimethyl-formamide;