(4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

Base Information

Chemical Name:(4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester
CAS No.:1602923-16-9
Molecular Formula:C₂₁H₂₁Cl₂F₃N₂O₂
Molecular Weight:461.311
Hs Code.:

Synonyms:(4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

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Technology Process of (4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

There total 2 articles about (4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1602924-08-2
3-(3-(4-chlorophenyl)piperidin-1-yl)-1,1,1-trifluoropropan-2-ol

: 104-12-1
p-chlorphenylisocyanate

: 1602923-16-9
(4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

Guidance literature:: In dichloromethane; acetonitrile; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 55989-13-4
(RS)-3-(4-chlorophenyl)piperidine

: 1602923-16-9
(4-chlorophenyl)-carbamic acid 1-[3-(4-chlorophenyl)-piperidin-1-ylmethyl]-2,2,2-trifluoro ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane; acetonitrile / 20 °C / Inert atmosphere

2: dichloromethane; acetonitrile / 1 h / 20 °C / Inert atmosphere

In dichloromethane; acetonitrile;