ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate

Base Information

Chemical Name:ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate
CAS No.:24393-46-2
Molecular Formula:C₁₄H₁₅NO₄
Molecular Weight:261.277
Hs Code.:
DSSTox Substance ID:DTXSID501205462
Nikkaji Number:J3.152.762G

Synonyms:ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate;DTXSID501205462;HMS1664N04;SMSF0003659;AKOS000957695;CCG-237724;BIM-0009077.P001;(E)-Ethyl 2-cyano-3-(2,4-dimethoxyphenyl)prop-2-enoate;2-Cyano-3-(2,4-dimethoxyphenyl)propenoic acid ethyl ester;24393-46-2

Suppliers and Price of ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:261.10010796
Heavy Atom Count:19
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(=CC1=C(C=C(C=C1)OC)OC)C#N
Isomeric SMILES:CCOC(=O)/C(=C/C1=C(C=C(C=C1)OC)OC)/C#N

Technology Process of ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate

There total 1 articles about ethyl (2E)-2-cyano-3-(2,4-dimethoxyphenyl)-2-propenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 105-56-6
ethyl 2-cyanoacetate

: 613-45-6
2,4-Dimethoxybenzaldehyde

: 24393-46-2
ethyl (E)-2-cyano-3-(2',4'-dimethoxyphenyl)prop-2-enoate

Guidance literature:: With sodium carbonate; at 26 ℃; Neat (no solvent);

Reference yield:

: 503-87-7
2-thiohydantoin

: 24393-46-2
ethyl (E)-2-cyano-3-(2',4'-dimethoxyphenyl)prop-2-enoate

: 224312-87-2,326905-20-8
(5Z)-5-(2,4-dimethoxy-benzylidene)-2-thioxo-imidazolidin-4-one

Guidance literature:: With piperidine; In ethanol; at 80 - 90 ℃;
DOI:10.1515/HC.2005.11.5.433

Reference yield:

: 24393-46-2
ethyl (E)-2-cyano-3-(2',4'-dimethoxyphenyl)prop-2-enoate

: (5Z)-5-(2,4-dimethoxybenzylidene)-3-(4-nitrobenzyl)-2-thioxo-imidazolidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / ethanol / 80 - 90 °C

2: 79 percent / K₂CO₃ / methanol / 20 °C

With piperidine; potassium carbonate; In methanol; ethanol;
DOI:10.1515/HC.2005.11.5.433