(Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

Base Information

Chemical Name:(Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate
CAS No.:855778-38-0
Molecular Formula:C₂₀H₂₂N₂O₄
Molecular Weight:354.406
Hs Code.:

Synonyms:(Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

Suppliers and Price of (Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 17 raw suppliers

Chemical Property of (Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

Chemical Property:

Purity/Quality:: 99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

There total 1 articles about (Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87-62-7
2,6-dimethylaniline

: 890044-57-2
(E)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

: 855778-38-0
(Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: Iodine monochloride; sodium hydrogencarbonate / methanol; dichloromethane / 4 h / 20 °C

1.2: -15 °C

2.1: triethylamine; palladium diacetate; tetrabutyl-ammonium chloride / tetrahydrofuran / 3.5 h / 80 °C / Inert atmosphere; Reflux

With tetrabutyl-ammonium chloride; palladium diacetate; Iodine monochloride; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; 2.1: |Heck Reaction;

Reference yield: 98.0%

: 855778-38-0
(Z)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonylamino)acrylate

: 855778-39-1
(R)-methyl 3-(4-amino-3,5-dimethylphenyl)-2-(benzyloxycarbonyl)propanoate

Guidance literature:: With hydrogen; (Z,Z)-cycloocta-1,5-diene(R,R-1,2-bis(2,5-diethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; In methanol; dichloromethane; at 20 ℃; for 16h; under 3102.97 - 3361.55 Torr;